Cassia Overk
Overview
Explore the profile of Cassia Overk including associated specialties, affiliations and a list of published articles.
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Articles
24
Citations
402
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0
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Recent Articles
1.
El-Agnaf O, Overk C, Rockenstein E, Mante M, Florio J, Adame A, et al.
Neurobiol Dis
. 2025 Jan;
206:106788.
PMID: 39818529
No abstract available.
2.
Iba M, Kwon S, Kim C, Szabo M, Horan-Portelance L, Lopez-Ocasio M, et al.
J Neuroinflammation
. 2024 Apr;
21(1):93.
PMID: 38622654
The neuroinflammatory process in synucleinopathies of the aging population such as Parkinson's disease (PD) and dementia with Lewy bodies (DLB) involves microglial activation as well as infiltration of the CNS...
3.
Fares M, Alijevic O, Johne S, Overk C, Hashimoto M, Kondylis A, et al.
Front Neurosci
. 2023 Sep;
17:1239009.
PMID: 37719154
Introduction: Alpha-synuclein (α-Syn) aggregation, transmission, and contribution to neurotoxicity represent central mechanisms underlying Parkinson's disease. The plant alkaloid "nicotine" was reported to attenuate α-Syn aggregation in different models, but its...
4.
Overk C, Fiorini E, Babolin C, Vukicevic M, Morici C, Madani R, et al.
Front Neurosci
. 2023 Jul;
17:1202208.
PMID: 37449271
Introduction: People with DS are highly predisposed to Alzheimer's disease (AD) and demonstrate very similar clinical and pathological features. Ts65Dn mice are widely used and serve as the best-characterized animal...
5.
Iba M, Kim C, Kwon S, Szabo M, Horan-Portelance L, Peer C, et al.
Sci Transl Med
. 2023 May;
15(695):eabq6089.
PMID: 37163617
Alterations in the p38 mitogen-activated protein kinases (MAPKs) play an important role in the pathogenesis of dementia with Lewy bodies (DLB) and Parkinson's disease (PD). Activation of the p38α MAPK...
6.
Spencer B, Rissman R, Overk C, Masliah E
Methods Mol Biol
. 2021 Nov;
2383:447-457.
PMID: 34766306
Alzheimer's disease (AD), Pick's disease, fronto-temporal lobar degeneration, cortico-basal degeneration, and primary age related tauopathy are examples of neurodegenerative disorders with tau accumulation and jointly referred as "tauopathies." The mechanisms...
7.
Sawa M, Overk C, Becker A, Derse D, Albay R, Weldy K, et al.
Alzheimers Dement
. 2021 Nov;
18(6):1203-1234.
PMID: 34757693
Introduction: People with Down syndrome (DS) are predisposed to Alzheimer's disease (AD). The amyloid hypothesis informs studies of AD. In AD-DS, but not sporadic AD, increased APP copy number is...
8.
Chen X, Salehi A, Pearn M, Overk C, Nguyen P, Kleschevnikov A, et al.
Alzheimers Dement
. 2020 Sep;
17(2):271-292.
PMID: 32975365
Objective: Recent clinical trials targeting amyloid beta (Aβ) and tau in Alzheimer's disease (AD) have yet to demonstrate efficacy. Reviewing the hypotheses for AD pathogenesis and defining possible links between...
9.
Iba M, Kim C, Sallin M, Kwon S, Verma A, Overk C, et al.
J Neuroinflammation
. 2020 Jul;
17(1):214.
PMID: 32680537
Background: α-Synuclein (α-syn) is a pre-synaptic protein which progressively accumulates in neuronal and non-neuronal cells in neurodegenerative diseases such as Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple...
10.