Caryn S Ross-Innes
Overview
Explore the profile of Caryn S Ross-Innes including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
16
Citations
3130
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Ross-Innes C, Chettouh H, Achilleos A, Galeano-Dalmau N, Debiram-Beecham I, MacRae S, et al.
Lancet Gastroenterol Hepatol
. 2017 Apr;
2(1):23-31.
PMID: 28404010
Background: Barrett's oesophagus predisposes to adenocarcinoma. However, most patients with Barrett's oesophagus will not progress and endoscopic surveillance is invasive, expensive, and fraught by issues of sampling bias and the...
2.
Varghese S, Newton R, Ross-Innes C, Lao-Sirieix P, Krishnadath K, ODonovan M, et al.
Gastroenterology
. 2015 Aug;
149(6):1511-1518.e5.
PMID: 26248086
Background & Aims: Diagnoses of dysplasia, based on histologic analyses, dictate management decisions for patients with Barrett's esophagus (BE). However, there is much intra- and inter-observer variation in identification of...
3.
Ross-Innes C, Becq J, Warren A, Cheetham R, Northen H, ODonovan M, et al.
Nat Genet
. 2015 Jul;
47(9):1038-1046.
PMID: 26192915
The molecular genetic relationship between esophageal adenocarcinoma (EAC) and its precursor lesion, Barrett's esophagus, is poorly understood. Using whole-genome sequencing on 23 paired Barrett's esophagus and EAC samples, together with...
4.
Ross-Innes C, Debiram-Beecham I, ODonovan M, Walker E, Varghese S, Lao-Sirieix P, et al.
PLoS Med
. 2015 Jan;
12(1):e1001780.
PMID: 25634542
Background: Barrett's esophagus (BE) is a commonly undiagnosed condition that predisposes to esophageal adenocarcinoma. Routine endoscopic screening for BE is not recommended because of the burden this would impose on...
5.
Weaver J, Ross-Innes C, Shannon N, Lynch A, Forshew T, Barbera M, et al.
Nat Genet
. 2014 Jun;
46(8):837-843.
PMID: 24952744
Cancer genome sequencing studies have identified numerous driver genes, but the relative timing of mutations in carcinogenesis remains unclear. The gradual progression from premalignant Barrett's esophagus to esophageal adenocarcinoma (EAC)...
6.
Ong C, Shannon N, Ross-Innes C, ODonovan M, Rueda O, Hu D, et al.
J Natl Cancer Inst
. 2014 Apr;
106(5).
PMID: 24777112
Background: Many prognostic biomarkers have been proposed recently. However, there is a lack of therapeutic strategies exploiting novel prognostic biomarkers. We aimed to propose therapeutic options in patients with overexpression...
7.
Weaver J, Ross-Innes C, Fitzgerald R
Nat Rev Gastroenterol Hepatol
. 2013 Aug;
11(1):19-27.
PMID: 23982683
Oesophageal adenocarcinoma (OAC) is the eighth most common cancer type worldwide with a dismal 5-year survival. Barrett oesophagus, the replacement of the normal squamous epithelia with glandular cells, is the...
8.
Mohammed H, DSantos C, Serandour A, Ali H, Brown G, Atkins A, et al.
Cell Rep
. 2013 Feb;
3(2):342-9.
PMID: 23403292
Estrogen receptor-α (ER) is the driving transcription factor in most breast cancers, and its associated proteins can influence drug response, but direct methods for identifying interacting proteins have been limited....
9.
Sanders D, Ross-Innes C, Beraldi D, Carroll J, Balasubramanian S
Genome Biol
. 2013 Jan;
14(1):R6.
PMID: 23347430
Background: The forkhead transcription factor FOXM1 is a key regulator of the cell cycle. It is frequently over-expressed in cancer and is emerging as an important therapeutic target. In breast...
10.
Ross-Innes C, Stark R, Teschendorff A, Holmes K, Ali H, Dunning M, et al.
Nature
. 2012 Jan;
481(7381):389-93.
PMID: 22217937
Oestrogen receptor-α (ER) is the defining and driving transcription factor in the majority of breast cancers and its target genes dictate cell growth and endocrine response, yet genomic understanding of...