Caryn S Ross-Innes
Overview
Explore the profile of Caryn S Ross-Innes including associated specialties, affiliations and a list of published articles.
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16
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3130
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Recent Articles
11.
Ross-Innes C, Brown G, Carroll J
BMC Genomics
. 2011 Dec;
12:593.
PMID: 22142239
Background: CCCTC-binding factor (CTCF) is a conserved zinc finger transcription factor that is involved in both intra- and interchromasomal looping. Recent research has shown a role for CTCF in estrogen...
12.
Robinson J, MacArthur S, Ross-Innes C, Tilley W, Neal D, Mills I, et al.
EMBO J
. 2011 Jun;
30(15):3019-27.
PMID: 21701558
Breast cancer is a heterogeneous disease and several distinct subtypes exist based on differential gene expression patterns. Molecular apocrine tumours were recently identified as an additional subgroup, characterised as oestrogen...
13.
Holmes K, Hurtado A, Brown G, Launchbury R, Ross-Innes C, Hadfield J, et al.
Proc Natl Acad Sci U S A
. 2011 May;
109(8):2748-53.
PMID: 21536917
Estrogen receptor (ER) binds to distal enhancers within the genome and requires additional factors, such as the Forkhead protein FoxA1, for mediating chromatin interactions. We now show that the human...
14.
Hurtado A, Holmes K, Ross-Innes C, Schmidt D, Carroll J
Nat Genet
. 2010 Dec;
43(1):27-33.
PMID: 21151129
Estrogen receptor-α (ER) is the key feature of most breast cancers and binding of ER to the genome correlates with expression of the Forkhead protein FOXA1 (also called HNF3α). Here...
15.
Schmidt D, Schwalie P, Ross-Innes C, Hurtado A, Brown G, Carroll J, et al.
Genome Res
. 2010 Mar;
20(5):578-88.
PMID: 20219941
The cohesin protein complex holds sister chromatids in dividing cells together and is essential for chromosome segregation. Recently, cohesin has been implicated in mediating transcriptional insulation, via its interactions with...
16.
Ross-Innes C, Stark R, Holmes K, Schmidt D, Spyrou C, Russell R, et al.
Genes Dev
. 2010 Jan;
24(2):171-82.
PMID: 20080953
Retinoic acid receptor-alpha (RAR alpha) is a known estrogen target gene in breast cancer cells. The consequence of RAR alpha induction by estrogen was previously unknown. We now show that...