Carson C Chow
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Explore the profile of Carson C Chow including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Trzaskoma P, Jung S, Kanno Y, OShea J, Chow C
Neoplasia
. 2024 Oct;
58:101071.
PMID: 39405604
Chemotherapy, although effective in treating cancer, can induce various cellular responses, including senescence and drug resistance. Here, we investigate the transcriptomic alterations induced by doxorubicin (DOX), a commonly used chemotherapeutic...
2.
Kim C, Chow C, Averbeck B
bioRxiv
. 2024 Oct;
PMID: 39372802
In probabilistic reversal learning, the choice option yielding reward at higher probability switches at a random trial. To perform optimally in this task, one has to accumulate evidence across trials...
3.
Trzaskoma P, Jung S, Pekowska A, Bohrer C, Wang X, Naz F, et al.
Sci Adv
. 2024 Aug;
10(32):eadl4893.
PMID: 39121214
Discontinuous transcription is evolutionarily conserved and a fundamental feature of gene regulation; yet, the exact mechanisms underlying transcriptional bursting are unresolved. Analyses of bursting transcriptome-wide have focused on the role...
4.
Chang T, Xia H, Mahajan S, Mahajan R, Maisog J, Vattikuti S, et al.
PLoS One
. 2024 May;
19(5):e0302871.
PMID: 38722929
We developed an inherently interpretable multilevel Bayesian framework for representing variation in regression coefficients that mimics the piecewise linearity of ReLU-activated deep neural networks. We used the framework to formulate...
5.
Chang J, Li X, Xu S, Yao H, Porcino J, Chow C
ArXiv
. 2024 May;
PMID: 38711425
We introduce gradient-flow-guided adaptive importance sampling (IS) transformations for stabilizing Monte-Carlo approximations of leave-one-out (LOO) cross-validated predictions for Bayesian models. After defining two variational problems, we derive corresponding simple nonlinear...
6.
Ranard B, Chow C, Megjhani M, Asgari S, Park S, Vodovotz Y
J Med Virol
. 2023 Jun;
95(6):e28854.
PMID: 37287404
Nirmatrelvir/ritonavir (Paxlovid), an oral antiviral medication targeting SARS-CoV-2, remains an important treatment for COVID-19. Initial studies of nirmatrelvir/ritonavir were performed in SARS-CoV-2 unvaccinated patients without prior confirmed SARS-CoV-2 infection; however,...
7.
Kim C, Finkelstein A, Chow C, Svoboda K, Darshan R
Nat Commun
. 2023 May;
14(1):2851.
PMID: 37202424
Task-related neural activity is widespread across populations of neurons during goal-directed behaviors. However, little is known about the synaptic reorganization and circuit mechanisms that lead to broad activity changes. Here...
8.
Shea K, Borchering R, Probert W, Howerton E, Bogich T, Li S, et al.
Proc Natl Acad Sci U S A
. 2023 Apr;
120(18):e2207537120.
PMID: 37098064
Policymakers must make management decisions despite incomplete knowledge and conflicting model projections. Little guidance exists for the rapid, representative, and unbiased collection of policy-relevant scientific input from independent modeling teams....
9.
Phillips J, Moret M, Zebende G, Chow C
Physica A
. 2022 Apr;
598:127318.
PMID: 35431416
The novel coronavirus SARS CoV-2 responsible for the COVID-19 pandemic and SARS CoV-1 responsible for the SARS epidemic of 2002-2003 share an ancestor yet evolved to have much different transmissibility...
10.
Day J, Park S, Ranard B, Singh H, Chow C, Vodovotz Y
Front Immunol
. 2021 Nov;
12:754127.
PMID: 34777366
COVID-19 presentations range from mild to moderate through severe disease but also manifest with persistent illness or viral recrudescence. We hypothesized that the spectrum of COVID-19 disease manifestations was a...