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Carolyn A Thomson

Explore the profile of Carolyn A Thomson including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 392
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Recent Articles
1.
Zucoloto A, Schlechte J, Ignacio A, Thomson C, Pyke S, Yu I, et al.
Cell Rep . 2023 May; 42(5):112507. PMID: 37195866
During bloodstream infections, neutrophils home to the liver as part of an intravascular immune response to eradicate blood-borne pathogens, but the mechanisms regulating this crucial response are unknown. Using in ...
2.
Brown K, Thomson C, Wacker S, Drikic M, Groves R, Fan V, et al.
Nat Commun . 2023 Mar; 14(1):1348. PMID: 36906623
Commensal bacteria are major contributors to mammalian metabolism. We used liquid chromatography mass spectrometry to study the metabolomes of germ-free, gnotobiotic, and specific-pathogen-free mice, while also evaluating the influence of...
3.
Thomson C, Morgan S, Ohland C, McCoy K
Mucosal Immunol . 2022 Sep; 15(6):1085-1094. PMID: 36065057
The gut microbiota influences host responses at practically every level, and as research into host-microbe interactions expands, it is not surprising that we are uncovering similar roles for the microbiota...
4.
Ignacio A, Shah K, Bernier-Latmani J, Koller Y, Coakley G, Moyat M, et al.
Immunity . 2022 Jun; 55(7):1250-1267.e12. PMID: 35709757
The intestine harbors a large population of resident eosinophils, yet the function of intestinal eosinophils has not been explored. Flow cytometry and whole-mount imaging identified eosinophils residing in the lamina...
5.
Davoli-Ferreira M, Thomson C, McCoy K
Front Immunol . 2021 Jun; 12:676255. PMID: 34113350
Autism spectrum disorders (ASD) are serious, highly variable neurodevelopmental disorders, commonly characterized by the manifestation of specific behavioral abnormalities, such as stereotypic behaviors and deficits in social skills, including communication....
6.
Thomson C, McColl A, Graham G, Cavanagh J
J Neuroinflammation . 2020 Mar; 17(1):94. PMID: 32213184
Background: Recent years have seen an explosion of research pertaining to biological psychiatry, yet despite subsequent advances in our understanding of neuroimmune communication pathways, how the brain senses and responds...
7.
Thomson C, Nibbs R, McCoy K, Mowat A
Immunology . 2020 Mar; 160(4):313-324. PMID: 32181492
The intestine is continuously exposed to an enormous variety and quantity of antigens and innate immune stimuli derived from both pathogens and harmless materials, such as food and commensal bacteria....
8.
Wyss M, Brown K, Thomson C, Koegler M, Terra F, Fan V, et al.
Front Immunol . 2020 Feb; 10:3107. PMID: 32010146
Early life exposure to microbes plays an important role in immune system development. Germ-free mice, or mice colonized with a low-diversity microbiota, exhibit high serum IgE levels. An increase in...
9.
Thomson C, McCoy K
Immunity . 2019 Jul; 51(1):12-14. PMID: 31315030
Appropriate priming of tolerogenic or effector immune responses is crucial for intestinal homeostasis. Recently in Nature, Esterházy et al. (2019) reveal how compartmentalization of lymphatic drainage to functionally distinct lymph...
10.
Scott N, Andrusaite A, Andersen P, Lawson M, Alcon-Giner C, Leclaire C, et al.
Sci Transl Med . 2018 Oct; 10(464). PMID: 30355800
Macrophages in the healthy intestine are highly specialized and usually respond to the gut microbiota without provoking an inflammatory response. A breakdown in this tolerance leads to inflammatory bowel disease...