Aline Ignacio
Overview
Explore the profile of Aline Ignacio including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
385
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0
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Recent Articles
1.
Ignacio A, Czyz S, McCoy K
Semin Immunol
. 2024 May;
73:101885.
PMID: 38788491
The gut microbiota is well known to possess immunomodulatory capacities, influencing a multitude of cellular signalling pathways to maintain host homeostasis. Although the formation of the immune system initiates before...
2.
Ignacio A, Cipelli M, Takiishi T, Aguiar C, Fernandes Terra F, Ghirotto B, et al.
J Leukoc Biol
. 2024 Apr;
116(4):779-792.
PMID: 38652699
The mammalian target of rapamycin (mTOR) pathway plays a key role in determining immune cells function through modulation of their metabolic status. By specific deletion of Rictor in CD11c+ myeloid...
3.
Zucoloto A, Schlechte J, Ignacio A, Thomson C, Pyke S, Yu I, et al.
Cell Rep
. 2023 May;
42(5):112507.
PMID: 37195866
During bloodstream infections, neutrophils home to the liver as part of an intravascular immune response to eradicate blood-borne pathogens, but the mechanisms regulating this crucial response are unknown. Using in ...
4.
Ignacio A, Shah K, Bernier-Latmani J, Koller Y, Coakley G, Moyat M, et al.
Immunity
. 2022 Jun;
55(7):1250-1267.e12.
PMID: 35709757
The intestine harbors a large population of resident eosinophils, yet the function of intestinal eosinophils has not been explored. Flow cytometry and whole-mount imaging identified eosinophils residing in the lamina...
5.
de Souza Breda C, Breda L, Carvalho L, Amano M, Fernandes Terra F, Silva R, et al.
J Immunol
. 2021 Jul;
207(2):626-639.
PMID: 34261666
Sepsis is a complex infectious syndrome in which neutrophil participation is crucial for patient survival. Neutrophils quickly sense and eliminate the pathogen by using different effector mechanisms controlled by metabolic...
6.
Shah K, Ignacio A, McCoy K, Harris N
Mucosal Immunol
. 2020 Mar;
13(4):574-583.
PMID: 32157190
Eosinophils are granulocytes, typically implicated as end-stage effector cells in type-II immune responses. They are capable of producing a wide array of pre-formed molecules which render them with vast potential...
7.
de Aguiar C, Castoldi A, Amano M, Ignacio A, Fernandes Terra F, Cruz M, et al.
Inflamm Bowel Dis
. 2019 Dec;
26(5):697-708.
PMID: 31819985
Background: The gut microbiota is a key element to support host homeostasis and the development of the immune system. The relationship between the microbiota and immunity is a 2-way road,...
8.
McCoy K, Ignacio A, Geuking M
Curr Opin Immunol
. 2018 Jun;
54:20-27.
PMID: 29864675
The trillions of microbes that colonize mucosal surfaces are critical for educating the immune system and microbial-derived signals continually shape and set the tone of immune responses. Although Type 2...
9.
Peres Leal M, Brochetti R, Ignacio A, Camara N, da Palma R, de Oliveira L, et al.
Toxicol Rep
. 2018 Jun;
5:512-520.
PMID: 29854623
Environmental and Occupational pollution has been extensively studied because of its serious implications on the human health. Formaldehyde (FA) is a pollutant widely employed in several industries and also in...
10.
de Aguiar C, Castoldi A, Andrade-Oliveira V, Ignacio A, da Cunha F, Felizardo R, et al.
Inflammopharmacology
. 2017 Oct;
26(1):251-260.
PMID: 29063489
Inflammatory bowel diseases (IBDs) affect millions of people worldwide and their frequencies in developed countries have increased since the twentieth century. In this context, there is an intensive search for...