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Carlos Rangel Rodrigues

Explore the profile of Carlos Rangel Rodrigues including associated specialties, affiliations and a list of published articles. Areas
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Articles 82
Citations 425
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Recent Articles
1.
Pereira G, Da Conceicao L, Abrahim-Vieira B, Rodrigues C, Cabral L, Coelho R, et al.
ACS Omega . 2025 Mar; 10(8):8349-8360. PMID: 40060867
Millions of new mutations have been discovered largely due to advancements in genome projects, but characterizing their effects through traditional wet-lab experiments remains labor-intensive and time-consuming. Functional prediction algorithms offer...
2.
Camargo P, da Silva R, Zuma A, Garden S, Albuquerque M, Rodrigues C, et al.
Sci Rep . 2025 Feb; 15(1):6036. PMID: 39971997
Based on the in vitro trypanocidal efficacy of previously synthesized N-aryl-1,10-phenanthroline-2-amines (Phen1-20) (aryl = R-phenyl, 1- or 2-naphthyl), we explored the potential interactions of these derivatives as ligands of our...
3.
Viana G, Cunha-Junior E, Assumpcao P, Rezende M, Emiliano Y, Soares L, et al.
Pharmaceuticals (Basel) . 2025 Jan; 17(12. PMID: 39770415
Leishmaniasis, caused by protozoa and transmitted by vectors, presents varied clinical manifestations based on parasite species and host immunity. The lack of effective vaccines or treatments has prompted research into...
4.
Camargo P, Suzukawa H, Pereira P, Silva M, Macedo Jr F, Albuquerque M, et al.
Sci Rep . 2025 Jan; 15(1):465. PMID: 39748011
This work investigates the anti-trypanosomal activities of ten thiohydantoin derivatives against the parasite Trypanosoma cruzi. Compounds with aliphatic chains (THD1, THD3, and THD5) exhibited the most promising IC against the...
5.
da Silva Bortoleti B, Camargo P, Goncalves M, Tomiotto-Pellissier F, Silva T, Concato V, et al.
Chem Biol Interact . 2024 Sep; 403:111216. PMID: 39218371
Leishmaniasis is a neglected tropical disease caused by parasites of the genus Leishmania and is responsible for more than 1 million new cases and 70,000 deaths annually worldwide. Treatment has...
6.
Vanzan D, Goma E, Locatelli F, da Silva Honorio T, de Souza Furtado P, Rodrigues C, et al.
Pharmaceutics . 2024 May; 16(5). PMID: 38794280
Silybin (SIB) is a hepatoprotective drug known for its poor oral bioavailability, attributed to its classification as a class IV drug with significant metabolism during the first-pass effect. This study...
7.
Camargo P, Dos Santos C, Albuquerque M, Rodrigues C, Lima C
Sci Rep . 2024 May; 14(1):11575. PMID: 38773273
Leishmaniasis is a disease caused by a protozoan of the genus Leishmania, affecting millions of people, mainly in tropical countries, due to poor social conditions and low economic development. First-line...
8.
de Souza Furtado P, Viana G, de Oliveira A, Rabelo V, Cerqueira I, Paschoal C, et al.
Curr Med Chem . 2024 Feb; 32(4):806-824. PMID: 38310396
Introduction: Thrombotic disorders are among the leading causes of morbidity and mortality worldwide. Drugs used in the prevention and treatment of atherothrombosis have pharmacokinetic limitations and adverse effects such as...
9.
da Silva Honorio T, Simon A, Machado R, Rodrigues C, do Carmo F, Cabral L, et al.
Curr Pharm Des . 2023 Nov; 29(38):3040-3049. PMID: 37957861
Background: Oral suspensions are heterogeneous disperse systems, and the particle size distribution, crystalline form of the dispersed solid, and composition of the formulation can be listed as parameters that control...
10.
Machado F, Folly D, Esteves R, Ruppelt B, da Silva V, Matos A, et al.
Molecules . 2023 Aug; 28(16). PMID: 37630195
Schistosomiasis is a tropical disease transmitted in an aqueous environment by cercariae from the genus. This disease affects 200 million people living in risk areas around the world. The control...