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Carl Herrmann

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Articles 66
Citations 3442
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Recent Articles
1.
Wurth R, Donato E, Michel L, Saini M, Becker L, Cheytan T, et al.
Nat Cancer . 2025 Jan; 6(1):67-85. PMID: 39753722
Circulating tumor cells (CTCs) drive metastasis, the leading cause of death in individuals with breast cancer. Due to their low abundance in the circulation, robust CTC expansion protocols are urgently...
2.
Karkar S, Sharma A, Herrmann C, Blum Y, Richard M
Bioinform Adv . 2024 Oct; 4(1):vbae136. PMID: 39411450
Summary: Unsupervised deconvolution algorithms are often used to estimate cell composition from bulk tissue samples. However, applying cell-type deconvolution and interpreting the results remain a challenge, even more without prior...
3.
Guo C, Sharma A, Guzman J, Herrmann C, Boulant S, Stanifer M
J Interferon Cytokine Res . 2024 Jul; 44(10):438-452. PMID: 39076109
Interferon lambdas (IFN-λs) are crucial to control virus infections at mucosal surfaces. Interleukin-22 (IL-22) was reported to help IFN-λ control rotavirus infection in the intestinal epithelium of mice either by...
4.
Bosch M, Kallin N, Donakonda S, Zhang J, Wintersteller H, Hegenbarth S, et al.
Nature . 2024 Jul; 631(8022):867-875. PMID: 38987588
Chronic hepatitis B virus (HBV) infection affects 300 million patients worldwide, in whom virus-specific CD8 T cells by still ill-defined mechanisms lose their function and cannot eliminate HBV-infected hepatocytes. Here...
5.
Zhang Y, Bharadhwaj V, Kodamullil A, Herrmann C
Discov Ment Health . 2024 Apr; 4(1):11. PMID: 38573526
The clinical burden of mental illness, in particular schizophrenia and bipolar disorder, are driven by frequent chronic courses and increased mortality, as well as the risk for comorbid conditions such...
6.
Bessonneau-Gaborit V, Cruard J, Guerin-Charbonnel C, Derrien J, Alberge J, Douillard E, et al.
Life Sci Alliance . 2023 Jul; 6(9). PMID: 37524526
Among glucocorticoids (GCs), dexamethasone (Dex) is widely used in treatment of multiple myelomas. However, despite a definite benefit, all patients relapse. Moreover, the molecular basis of glucocorticoid efficacy remains elusive....
7.
Doncevic D, Herrmann C
Bioinformatics . 2023 Jun; 39(6). PMID: 37326971
Motivation: Variational autoencoders (VAEs) have rapidly increased in popularity in biological applications and have already successfully been used on many omic datasets. Their latent space provides a low-dimensional representation of...
8.
Rheinberger M, Costa A, Kampmann M, Glavas D, Shytaj I, Sreeram S, et al.
Cell Rep . 2023 Feb; 42(2):112110. PMID: 36790927
HIV-1 encounters the hierarchically organized host chromatin to stably integrate and persist in anatomically distinct latent reservoirs. The contribution of genome organization in HIV-1 infection has been largely understudied across...
9.
Thurmann L, Klos M, Mackowiak S, Bieg M, Bauer T, Ishaque N, et al.
Allergy . 2023 Jan; 78(6):1489-1506. PMID: 36704932
Background: Childhood asthma is a result of a complex interaction of genetic and environmental components causing epigenetic and immune dysregulation, airway inflammation and impaired lung function. Although different microarray based...
10.
Rheinbay E, Nielsen M, Abascal F, Wala J, Shapira O, Tiao G, et al.
Nature . 2023 Jan; 614(7948):E40. PMID: 36697832
No abstract available.