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Carl Davis

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Articles 43
Citations 769
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Recent Articles
1.
Gallego R, Cho-Schultz S, Del Bel M, Dechert-Schmitt A, Donaldson J, He M, et al.
J Med Chem . 2024 Dec; 67(24):22002-22038. PMID: 39651809
Hematopoietic progenitor kinase 1 (HPK1/MAP4K1) represents a high interest target for the treatment of cancer through an immune-mediated mechanism. Herein we present highlights of the drug discovery campaign within the...
2.
Gallego R, Scales S, Toledo C, Auth M, Bernier L, Berry M, et al.
J Med Chem . 2024 Nov; 67(21):19234-19246. PMID: 39499084
By virtue of its role in cellular proliferation, microtubule-associated serine/threonine kinase-like (MASTL) represents a novel target and a first-in-class (FIC) opportunity to provide a new impactful therapeutic agent to oncology...
3.
Gilbert R, Davis C, Gravel J, Ouwerkerk D
Microbiol Resour Announc . 2024 Mar; 13(4):e0101223. PMID: 38501784
We report the 2.78-Mb circular genome sequence of sp. strain YE332, isolated from a fermentation of bovine rumen fluid, supplied with leaf material from cv. Cunningham. This genome sequence consists...
4.
Davis S, Davis C, Patel N, Kubba H, Clement W
J Pediatr Surg . 2024 Mar; 59(6):1066-1071. PMID: 38429129
Background: Airway anomalies, symptoms and interventions are commonly reported in children with oesophageal atresia with tracheoesophageal fistula (OA/TOF). The purpose of this study was to assess the incidence of these...
5.
Saphire E, Salie Z, Ke Z, Halfmann P, DeWald L, McArdle S, et al.
Res Sq . 2024 Jan; PMID: 38196595
Monoclonal antibodies (mAbs) against Ebola virus (EBOV) glycoprotein (GP) are the standard of care for Ebola virus disease (EVD). Anti-GP mAbs targeting the stalk and membrane proximal external region (MPER)...
6.
Jordan S, Ryu S, Burchett W, Davis C, Jones R, Zhang S, et al.
J Pharm Sci . 2023 Dec; 113(3):826-835. PMID: 38042346
Tumor binding is an important parameter to derive unbound tumor concentration to explore pharmacokinetics (PK) and pharmacodynamics (PD) relationships for oncology disease targets. Tumor binding was evaluated using eleven matrices,...
7.
Johnstone A, Davis C, Roberts N, Sharp K
Arch Dis Child . 2023 May; 108(8):678-683. PMID: 37185083
Objective: The aim of this study was to evaluate the current evidence regarding the quality of life (QoL) of children and young people with anterior chest wall deformity (ACWD). Methods:...
8.
Jensen A, Davis C, Gray B
Semin Fetal Neonatal Med . 2022 Nov; 27(6):101404. PMID: 36437185
In neonates with cardiac and/or respiratory failure, extracorporeal membrane oxygenation (ECMO) continues to be an important method of respiratory and/or cardiovascular support where conventional treatments are failing. ECMO cannulation involves...
9.
Worwa G, Cooper T, Yeh S, Shantha J, Hischak A, Klim S, et al.
Commun Biol . 2022 Nov; 5(1):1204. PMID: 36352100
Despite increasing evidence that uveitis is common and consequential in survivors of Ebola virus disease (EVD), the host-pathogen determinants of the clinical phenotype are undefined, including the pathogenetic role of...
10.
Desikan R, Linderman S, Davis C, Zarnitsyna V, Ahmed H, Antia R
Front Immunol . 2022 Oct; 13:985478. PMID: 36263031
Currently, vaccines for SARS-CoV-2 and influenza viruses are updated if the new vaccine induces higher antibody-titers to circulating variants than current vaccines. This approach does not account for complex dynamics...