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Rafi Ahmed

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Articles 402
Citations 44827
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Recent Articles
1.
Hastie K, Salie Z, Ke Z, Halfmann P, DeWald L, McArdle S, et al.
Nat Commun . 2025 Feb; 16(1):1293. PMID: 39900911
Monoclonal antibodies (mAbs) against Ebola virus (EBOV) glycoprotein (GP) are the standard of care for Ebola virus disease (EVD). Anti-GP mAbs targeting the stalk and membrane proximal external region (MPER)...
2.
Obeng R, Nasti T, Martens K, Li P, Mariniello A, Chang D, et al.
BMJ Oncol . 2025 Jan; 3(1):e000328. PMID: 39886145
Objective: Immune checkpoint inhibitors (ICI) that block the programmed cell death 1 (PD-1) pathway have shown promise with limited benefit. We and others have shown in small patient cohorts that...
3.
McManus D, Valanparambil R, Medina C, Scharer C, McGuire D, Sobierajska E, et al.
Nature . 2025 Jan; PMID: 39778710
This study examines the origin and differentiation of stem-like CD8 T cells that are essential for sustained T cell immunity in chronic viral infections and cancer and also have a...
4.
Nguyen N, Linderman S, Fashina T, Devine M, Conrady C, Shantha J, et al.
Int Med Case Rep J . 2024 Dec; 17:1055-1061. PMID: 39719962
Purpose: To report cytokine/chemokine profiles of ocular fluid in two patients with herpetic uveitis. Methods: Cytokine and chemokine profiling of ocular fluid was performed in two patients with herpetic uveitis....
5.
Li K, Cardenas-Lizana P, Lyu J, Kellner A, Li M, Cong P, et al.
Nat Commun . 2024 Sep; 15(1):8339. PMID: 39333505
Despite the success of PD-1 blockade in cancer therapy, how PD-1 initiates signaling remains unclear. Soluble PD-L1 is found in patient sera and can bind PD-1 but fails to suppress...
6.
Somisetty M, Mack P, Hsu C, Huang Y, Gomez J, Rodilla A, et al.
Clin Lung Cancer . 2024 Aug; 25(7):612-618. PMID: 39122606
Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may be spread by individuals unaware they are infected. Such dissemination has heightened ramifications in cancer patients, who may need to visit...
7.
Sacristan C, Youngblood B, Lu P, Bally A, Xu J, McGary K, et al.
Cell Rep . 2024 Jul; 43(8):114547. PMID: 39083377
During chronic infection, virus-specific CD8 cytotoxic T lymphocytes (CTLs) progressively lose their ability to mount effective antiviral responses. This "exhaustion" is coupled to persistent upregulation of inhibitory receptor programmed death-1...
8.
Mack P, Hsu C, Rodilla A, Gomez J, Cagan J, Huang Y, et al.
Vaccines (Basel) . 2024 Jul; 12(7). PMID: 39066351
In patients with lung cancer (LC), understanding factors that impact the dynamics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) anti-spike antibody (SAb) titers over time is critical, but challenging,...
9.
Dull P, Achilles S, Ahmed R, Barnabas R, Campos N, Chirgwin K, et al.
Vaccine . 2024 Jul; 42(25):126100. PMID: 39004526
Cervical cancer is a major cause of morbidity and mortality globally with a disproportionate impact on women in low- and middle-income countries. In 2021, the World Health Organization (WHO) called...
10.
Khan M, Nasti T, Qian J, Kleber T, Switchenko J, Kaufman J, et al.
Lancet Haematol . 2024 May; 11(7):e510-e520. PMID: 38797190
Background: Currently, the use of radiotherapy alone for people with multiple myeloma is limited to palliation of pain, pending fracture, and control of spinal-cord compression. Single immune-checkpoint inhibitors, such as...