Caitlin E Mac Nair
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Explore the profile of Caitlin E Mac Nair including associated specialties, affiliations and a list of published articles.
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8
Citations
241
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Recent Articles
1.
Wurl J, Mac Nair C, Dietz J, Shestopalov V, Nickells R
Int J Mol Sci
. 2023 Nov;
24(21).
PMID: 37958624
Glial reactivity is considered a hallmark of damage-induced innate immune responses in the central nervous system. In the visual system, unilateral optic nerve damage elicits dramatic glial reactivity in the...
2.
Mac Nair C, Schlamp C, Montgomery A, Shestopalov V, Nickells R
J Neuroinflammation
. 2016 Apr;
13(1):93.
PMID: 27126275
Background: Retinal ganglion cell (RGC) soma death is a consequence of optic nerve damage, including in optic neuropathies like glaucoma. The activation of the innate immune network in the retina...
3.
Mac Nair C, Nickells R
Prog Mol Biol Transl Sci
. 2015 Aug;
134:343-63.
PMID: 26310164
Glaucoma is a group of optic neuropathies characterized by the degeneration of retinal ganglion cell axons and somas, ultimately preventing light signals in the retina from reaching the brain. Glaucoma...
4.
Mac Nair C, Fernandes K, Schlamp C, Libby R, Nickells R
J Neuroinflammation
. 2014 Nov;
11:194.
PMID: 25407441
Background: Glaucoma is an optic neuropathy that is characterized by the loss of retinal ganglion cells (RGCs) initiated by damage to axons in the optic nerve. The degeneration and death...
5.
Schlamp C, Montgomery A, Mac Nair C, Schuart C, Willmer D, Nickells R
Mol Vis
. 2013 Jul;
19:1387-96.
PMID: 23825918
Purpose: Retinal ganglion cells comprise a percentage of the neurons actually residing in the ganglion cell layer (GCL) of the rodent retina. This estimate is useful to extrapolate ganglion cell...
6.
Greene J, Lhost J, Hines P, Scarlotta M, Harris M, Burwitz B, et al.
J Virol
. 2013 Apr;
87(13):7382-92.
PMID: 23616658
The live attenuated simian immunodeficiency virus (SIV) SIVmac239Δnef is the most effective SIV/human immunodeficiency virus (HIV) vaccine in preclinical testing. An understanding of the mechanisms responsible for protection may provide...
7.
Janssen K, Mac Nair C, Dietz J, Schlamp C, Nickells R
Invest Ophthalmol Vis Sci
. 2013 Feb;
54(3):1805-15.
PMID: 23422829
Purpose: Retinal ganglion cells atrophy during the execution of the intrinsic apoptotic program. This process, which has been termed the apoptotic volume decrease (AVD) in other cell types, has not...
8.
Friedrich T, Piaskowski S, Leon E, Furlott J, Maness N, Weisgrau K, et al.
J Virol
. 2010 Mar;
84(10):5443-7.
PMID: 20219903
Human and simian immunodeficiency viruses (HIV and SIV) downregulate major histocompatibility complex class I (MHC-I) molecules from the surface of infected cells. Although this activity is conserved across viral isolates,...