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Thomas C Friedrich

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Articles 181
Citations 5543
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Recent Articles
1.
Li A, Coffey L, Mohr E, Raper J, Chahroudi A, Ausderau K, et al.
Lancet Microbe . 2025 Mar; :101030. PMID: 40024258
Zika virus, a mosquito-transmitted orthoflavivirus, has become a pathogen of global health concern ever since the virus caused an epidemic in Brazil in 2015 associated with approximately 700 000 laboratory-confirmed...
2.
Krabbe N, Mitzey A, Bhattacharya S, Razo E, Zeng X, Bekiares N, et al.
bioRxiv . 2024 Jun; PMID: 38853987
One Sentence Summary: Clade IIb Mpox virus infection of pregnant rhesus macaques results in vertical transmission from mother to fetus and adverse pregnancy outcomes.
3.
Shafer M, Bobholz M, Vuyk W, Gregory D, Roguet A, Haddock Soto L, et al.
Lancet Microbe . 2024 Mar; 5(4):e335-e344. PMID: 38484748
Background: The origin of novel SARS-CoV-2 spike sequences found in wastewater, without corresponding detection in clinical specimens, remains unclear. We sought to determine the origin of one such cryptic wastewater...
4.
Singh T, Miller I, Venkatayogi S, Webster H, Heimsath H, Eudailey J, et al.
mBio . 2024 Feb; 15(3):e0316023. PMID: 38349142
Importance: The Zika virus epidemic of 2015-2016 in the Americas revealed that this mosquito-transmitted virus could be congenitally transmitted during pregnancy and cause birth defects in newborns. Currently, there are...
5.
Machkovech H, Hahn A, Garonzik Wang J, Grubaugh N, Halfmann P, Johnson M, et al.
Lancet Infect Dis . 2024 Feb; 24(7):e453-e462. PMID: 38340735
SARS-CoV-2 causes persistent infections in a subset of individuals, which is a major clinical and public health problem that should be prioritised for further investigation for several reasons. First, persistent...
6.
Grunst M, Gil H, Grandea 3rd A, Snow B, Andrabi R, Nedellec R, et al.
PLoS Pathog . 2024 Jan; 20(1):e1011819. PMID: 38252675
Fc-mediated antibody effector functions, such as antibody-dependent cellular cytotoxicity (ADCC), can contribute to the containment HIV-1 replication but whether such activities are sufficient for protection is unclear. We previously identified...
7.
Wang H, Solomon J, Reza S, Yang H, Chu W, Crozier I, et al.
J Med Imaging (Bellingham) . 2023 Dec; 10(6):066004. PMID: 38090646
Purpose: We describe a method to identify repeatable liver computed tomography (CT) radiomic features, suitable for detection of steatosis, in nonhuman primates. Criteria used for feature selection exclude nonrepeatable features...
8.
Krabbe N, Razo E, Abraham H, Spanton R, Shi Y, Bhattacharya S, et al.
Front Immunol . 2023 Oct; 14:1267638. PMID: 37809089
Introduction: Zika virus (ZIKV) infection during pregnancy results in a spectrum of birth defects and neurodevelopmental deficits in prenatally exposed infants, with no clear understanding of why some pregnancies are...
9.
Jaeger A, Marano J, Riemersma K, Castaneda D, Pritchard E, Pritchard J, et al.
J Virol . 2023 Oct; 97(10):e0116223. PMID: 37800949
Previously, we modeled direct transmission chains of Zika virus (ZIKV) by serially passaging ZIKV in mice and mosquitoes and found that direct mouse transmission chains selected for viruses with increased...
10.
Boehm E, Jaeger A, Ries H, Castaneda D, Weiler A, Valencia C, et al.
PLoS Negl Trop Dis . 2023 Oct; 17(10):e0011674. PMID: 37782672
A promising candidate for arbovirus control and prevention relies on replacing arbovirus-susceptible Aedes aegypti populations with mosquitoes that have been colonized by the intracellular bacterium Wolbachia and thus have a...