C S Ramesha
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Explore the profile of C S Ramesha including associated specialties, affiliations and a list of published articles.
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31
Citations
775
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Recent Articles
1.
Jett M, Ramesha C, Brown C, Chiu S, Emmett C, Voronin T, et al.
J Pharmacol Exp Ther
. 1999 Feb;
288(3):1288-97.
PMID: 10027870
The marked analgesic efficacy of ketorolac in humans, relative to other nonsteroidal anti-inflammatory drugs (NSAIDs), has lead to speculation as to whether additional non-NSAID mechanism(s) contribute to its analgesic actions....
2.
Yu M, Ives D, Ramesha C
J Biol Chem
. 1997 Aug;
272(34):21181-6.
PMID: 9261124
Because of its structural similarity to polyunsaturated fatty acids, anandamide could serve as substrate for enzymes such as lipoxygenases and cyclooxygenases, which metabolize polyunsaturated fatty acids to potent bioactive metabolites....
3.
Swinney D, Mak A, Barnett J, Ramesha C
J Biol Chem
. 1997 May;
272(19):12393-8.
PMID: 9139685
Prostaglandins are synthesized by prostaglandin H synthase (PGHS) 1 and 2. PGHS2 is regulated through inducible expression. We report here the regulation of PGHS1 activity by substrate-dependent cooperative activation. The...
4.
5.
Ramesha C, Ives D
Biochim Biophys Acta
. 1993 May;
1168(1):37-44.
PMID: 8504140
The present report describes the presence of an arachidonic-acid-selective, dithiothreitol-insensitive phospholipase A2 enzyme activity in human neutrophil cytosol. The enzyme activity is eluted from Mono Q FPLC column between 350...
6.
Hoeck W, Ramesha C, Chang D, Fan N, Heller R
Proc Natl Acad Sci U S A
. 1993 May;
90(10):4475-9.
PMID: 8506288
The interaction of tumor necrosis factor alpha (TNF) with its two membrane-bound receptors initiates intracellular events in which arachidonic acid and its derivatives are involved. In HeLa cells, TNF treatment...
7.
Reid T, Ramesha C, Ringold G
J Biol Chem
. 1991 Sep;
266(25):16580-6.
PMID: 1909330
We have found that TA1-R6, which are resistant to the cytotoxic effects of tumor necrosis factor (TNF) in the presence of cycloheximide (Reid, T. R., Torti, F., and Ringold, G....
8.
Clark J, Lin L, Kriz R, Ramesha C, Sultzman L, Lin A, et al.
Cell
. 1991 Jun;
65(6):1043-51.
PMID: 1904318
We report the cloning and expression of a cDNA encoding a high molecular weight (85.2 kd) cytosolic phospholipase A2 (cPLA2) that has no detectable sequence homology with the secreted forms...
9.
Ramesha C, Taylor L
Anal Biochem
. 1991 Jan;
192(1):173-80.
PMID: 2048718
a simple gas chromatographic method for the assay of phospholipase A2 (PLA2) has been described in which arachidonic acid released from endogenous phospholipid pools is measured following its extraction and...
10.
Haliday E, Ramesha C, Ringold G
EMBO J
. 1991 Jan;
10(1):109-15.
PMID: 1899225
Tumour necrosis factor (TNF), a lymphokine released by activated macrophages, has diverse effects on a wide variety of cell types. TNF exerts these effects via specific cell surface receptors; however...