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C Pecqueur

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Articles 24
Citations 885
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Recent Articles
1.
Dollet L, Magre J, Joubert M, Le May C, Ayer A, Arnaud L, et al.
Sci Rep . 2016 Oct; 6:35487. PMID: 27748422
Loss-of-function mutations in BSCL2 are responsible for Berardinelli-Seip congenital lipodystrophy, a rare disorder characterized by near absence of adipose tissue associated with insulin resistance. Seipin-deficient (Bscl2) mice display an almost...
2.
Oizel K, Gratas C, Nadaradjane A, Oliver L, Vallette F, Pecqueur C
Cell Death Dis . 2015 Mar; 6:e1704. PMID: 25811801
Somatic mutations in isocitrate dehydrogenase (IDH)-1 and -2 have recently been described in glioma. This mutation leads to a neomorphic enzymatic activity as the conversion of isocitrate to alpha ketoglutarate...
3.
Morfouace M, Lalier L, Oliver L, Cheray M, Pecqueur C, Cartron P, et al.
Cell Death Dis . 2014 Feb; 5:e1036. PMID: 24481450
Glioma stem cells are highly resistant to cell death and as such are supposed to contribute to tumor recurrence by eluding anticancer treatments. Here, we show that spheroids that contain...
4.
Yakubu D, Mostyn A, Wilson V, Pearce S, Alves-Guerra M, Pecqueur C, et al.
Reproduction . 2007 Jul; 133(6):1241-52. PMID: 17636178
Adaptation to the extrauterine environment at birth relies upon the onset of postnatal function and increased metabolism in the lungs, liver and kidney, mediated partly by activation of mitochondrial proteins...
5.
Gnanalingham M, Mostyn A, Wang J, Webb R, Keisler D, Raver N, et al.
J Endocrinol . 2005 Oct; 187(1):81-8. PMID: 16214943
Many tissues undergo a rapid transition after birth, accompanied by dramatic changes in mitochondrial protein function. In particular, uncoupling protein (UCP) abundance increases at birth in the lung and adipose...
6.
Gnanalingham M, Mostyn A, Webb R, Keisler D, Raver N, Alves-Guerra M, et al.
Am J Physiol Endocrinol Metab . 2005 Aug; 289(6):E1093-100. PMID: 16091386
In the neonate, adipose tissue and the lung both undergo a rapid transition after birth, which results in dramatic changes in uncoupling protein abundance and glucocorticoid action. Leptin potentially mediates...
7.
Mostyn A, Litten J, Perkins K, Alves-Guerra M, Pecqueur C, Miroux B, et al.
J Endocrinol . 2004 Nov; 183(1):121-31. PMID: 15525580
The present study aimed to determine whether porcine genotype and/or postnatal age influenced mRNA abundance or protein expression of uncoupling protein (UCP)2 or 3 in subcutaneous adipose tissue (AT) and...
8.
Pearce S, Mostyn A, Alves-Guerra M, Pecqueur C, Miroux B, Webb R, et al.
Proc Nutr Soc . 2003 Sep; 62(2):421-7. PMID: 14506890
Uncoupling proteins (UCP) 1 and 2 are members of the subfamily of inner mitochondrial membrane carriers. UCP1 is specific to brown adipose tissue (BAT), where it is responsible for the...
9.
Mostyn A, Wilson V, Dandrea J, Yakubu D, Budge H, Alves-Guerra M, et al.
Br J Nutr . 2003 Aug; 90(2):323-8. PMID: 12908892
The present study examined the ontogeny of mitochondrial protein abundance in adipose tissue and lungs over the first month of life in the sheep and the extent to which this...
10.
Rousset S, Gelly C, Pecqueur C, Bouillaud F, Ricquier D
Int J Obes Relat Metab Disord . 2002 May; 26(5):735-8. PMID: 12032762
Uncoupling protein 1 (UCP1) is uniquely expressed in brown adipose tissue (BAT) and generates heat by uncoupling respiration from ATP synthesis. A defect in BAT thermogenesis has been described in...