C M Carthy
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Explore the profile of C M Carthy including associated specialties, affiliations and a list of published articles.
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21
Citations
418
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Recent Articles
1.
Matroule J, Carthy C, Granville D, Jolois O, Hunt D, Piette J
Oncogene
. 2001 Aug;
20(30):4070-84.
PMID: 11494135
Pyropheophorbide-a methylester (PPME) is a second generation of photosensitizers used in photodynamic therapy (PDT). We demonstrated that PPME photosensitization triggered apoptosis of colon cancer cells as measured by using several...
2.
Heczko U, Carthy C, OBrien B, Finlay B
Infect Immun
. 2001 Jun;
69(7):4580-9.
PMID: 11402002
Significant changes occur in intestinal epithelial cells after infection with enteropathogenic Escherichia coli (EPEC). However, it is unclear whether this pathogen alters rates of apoptosis. By using a naturally occurring...
3.
Wang A, Cheung P, Zhang H, Carthy C, Bohunek L, Wilson J, et al.
Antimicrob Agents Chemother
. 2001 Mar;
45(4):1043-52.
PMID: 11257014
The 5' and 3' untranslated regions (UTRs) of coxsackievirus B3 (CVB3) RNA form highly ordered secondary structures that have been confirmed to play important regulatory roles in viral cap-independent internal...
4.
McGarrity T, Peiffer L, Granville D, Carthy C, LEVY J, Khandelwal M, et al.
Cancer Lett
. 2001 Feb;
163(1):33-41.
PMID: 11163106
Tumor cell death in vitro by photodynamic therapy (PDT) has been related to the induction of apoptosis. We measured and compared changes in apoptosis and caspase 3 activity, an effector...
5.
McDonald T, Grinman M, Carthy C, Walley K
Am J Physiol Heart Circ Physiol
. 2000 Oct;
279(5):H2053-61.
PMID: 11045937
Inflammatory mediators of sepsis induce apoptosis in many cell lines. We tested the hypothesis that lipopolysaccharide (LPS) injection in vivo results in induction of early apoptotic and survival pathways as...
6.
Taylor L, Carthy C, Yang D, Saad K, Wong D, SCHREINER G, et al.
Circ Res
. 2000 Aug;
87(4):328-34.
PMID: 10948068
Host genetic responses that characterize enteroviral myocarditis have not yet been determined. The injurious and inflammatory process in heart muscle may reflect host responses of benefit to the virus and...
7.
Granville D, Carthy C, Jiang H, LEVY J, McManus B, Matroule J, et al.
Blood
. 1999 Dec;
95(1):256-62.
PMID: 10607710
The nuclear factor-kappa B (NF-kappaB) gene transactivator serves in the formation of immune, inflammatory, and stress responses. In quiescent cells, NF-kappaB principally resides within the cytoplasm in association with inhibitory...
8.
Liu Z, Carthy C, Cheung P, Bohunek L, Wilson J, McManus B, et al.
Virology
. 1999 Dec;
265(2):206-17.
PMID: 10600593
The lengthy 5' untranslated region (5'UTR) of coxsackievirus B3 (CVB3) forms a highly ordered secondary structure, which plays an important role in controlling viral transcription and translation. Our previous work...
9.
Granville D, Shaw J, Leong S, Carthy C, Margaron P, Hunt D, et al.
Am J Pathol
. 1999 Oct;
155(4):1021-5.
PMID: 10514382
Although the executioner phase of apoptosis has been well defined in many cell types, the subcellular events leading to apoptosis in endothelial cells remain undefined. In the current study, apoptosis...
10.
Carthy C, Granville D, Jiang H, LEVY J, Rudin C, Thompson C, et al.
Lab Invest
. 1999 Aug;
79(8):953-65.
PMID: 10462033
Certain nonmetallic porphyrins have potent antitumor activity upon visible light irradiation. Treatment of HeLa cells with nanomolar amounts of the photochemo therapeutic agent verteporfin and red light mobilized caspases 2,...