C Luberto
Overview
Explore the profile of C Luberto including associated specialties, affiliations and a list of published articles.
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19
Citations
770
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Recent Articles
1.
Signorelli P, Luberto C, Hannun Y
FASEB J
. 2001 Nov;
15(13):2401-14.
PMID: 11689465
Protein kinase C (PKC) is known to activate NF-kappaB whereas the lipid mediator ceramide was recently shown to inhibit activation of this transcription factor (1, 2). In this study, the...
2.
Ogretmen B, Schady D, Usta J, Wood R, Kraveka J, Luberto C, et al.
J Biol Chem
. 2001 May;
276(27):24901-10.
PMID: 11335714
This study was designed to analyze whether ceramide, a bioeffector of growth suppression, plays a role in the regulation of telomerase activity in A549 cells. Telomerase activity was inhibited significantly...
3.
Hannun Y, Luberto C, Argraves K
Biochemistry
. 2001 Apr;
40(16):4893-903.
PMID: 11305904
Many enzymes of sphingolipid metabolism are regulated in response to extra- and intracellular stimuli and in turn serve as regulators of levels of bioactive lipids (such as sphingosine, ceramide, sphingosine...
4.
Kroesen B, Pettus B, Luberto C, Busman M, Sietsma H, de Leij L, et al.
J Biol Chem
. 2001 Mar;
276(17):13606-14.
PMID: 11278517
B-cells, triggered via their surface B-cell receptor (BcR), start an apoptotic program known as activation-induced cell death (AICD), and it is widely believed that this phenomenon plays a role in...
5.
Luberto C, Toffaletti D, Wills E, Tucker S, Casadevall A, Perfect J, et al.
Genes Dev
. 2001 Feb;
15(2):201-12.
PMID: 11157776
Cryptococcus neoformans is a leading cause of life-threatening fungal infection in immunocompromised patients. Inositol-phosphoryl ceramide synthase 1 (Ipc1) is a fungus-specific enzyme, encoded by the essential IPC1 gene, that catalyzes...
6.
7.
Sawai H, Okamoto Y, Luberto C, Mao C, Bielawska A, Domae N, et al.
J Biol Chem
. 2000 Sep;
275(50):39793-8.
PMID: 11006294
Sphingolipids have emerged as novel bioactive mediators in eukaryotic cells including yeast. It has been proposed that sphingomyelin (SM) hydrolysis and the concomitant generation of ceramide are involved in various...
8.
Luberto C, Yoo D, Suidan H, Bartoli G, Hannun Y
J Biol Chem
. 2000 May;
275(19):14760-6.
PMID: 10799564
The precise role of ceramide in NF-kappaB signaling remains unclear. The recent observation of differential sphingomyelin synthase (SMS) activity in normal (low SMS) versus SV40-transformed (high SMS) WI38 human lung...
9.
van Tiel C, Luberto C, Snoek G, Hannun Y, Wirtz K
Biochem J
. 2000 Mar;
346 Pt 2:537-43.
PMID: 10677376
In order to study the in vivo function of the phosphatidylinositol transfer protein beta (PI-TPbeta), mouse NIH3T3 fibroblasts were transfected with cDNA encoding mouse PI-TPbeta. Two stable cell lines were...
10.
Hannun Y, Luberto C
Trends Cell Biol
. 2000 Feb;
10(2):73-80.
PMID: 10652518
Several extracellular agents and stress stimuli, such as tumour necrosis factor alpha, chemotherapeutic agents and heat, cause ceramide accumulation. They do this by regulating enzymes involved in its metabolism. Ceramide...