C J Ormandy
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Explore the profile of C J Ormandy including associated specialties, affiliations and a list of published articles.
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Articles
32
Citations
907
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Recent Articles
1.
Nair R, Roden D, Teo W, McFarland A, Junankar S, Ye S, et al.
Oncogene
. 2013 Sep;
33(30):3992-4002.
PMID: 24056965
The HER2 (ERBB2) and MYC genes are commonly amplified in breast cancer, yet little is known about their molecular and clinical interaction. Using a novel chimeric mammary transgenic approach and...
2.
Byrne F, Yang L, Phillips P, Hansford L, Fletcher J, Ormandy C, et al.
Oncogene
. 2013 Feb;
33(7):882-90.
PMID: 23396365
Metastatic neuroblastoma is an aggressive childhood cancer of neural crest origin. Stathmin, a microtubule destabilizing protein, is highly expressed in neuroblastoma although its functional role in this malignancy has not...
3.
Ortiz-Padilla C, Gallego-Ortega D, Browne B, Hochgrafe F, Caldon C, Lyons R, et al.
Oncogene
. 2012 Jul;
32(21):2696-702.
PMID: 22751113
Grb2-associated binder 1 (Gab1) is a docking protein that transduces signals from a variety of tyrosine kinases, including Met and the epidermal growth factor receptor (EGFR). Although the related protein...
4.
Hilton H, Kalyuga M, Cowley M, Alles M, Lee H, Caldon C, et al.
Mol Endocrinol
. 2010 Jun;
24(7):1380-92.
PMID: 20519331
Prolactin and progesterone act together to regulate mammary alveolar development, and both hormones have been implicated in breast cancer initiation and progression. Here we show that Elf5, a prolactin-induced ETS...
5.
Craven A, Nixon A, Ashby M, Ormandy C, Blazek K, Wilkins R, et al.
J Endocrinol
. 2006 Nov;
191(2):415-25.
PMID: 17088411
Mammalian hair growth is cyclic, with hair-producing follicles alternating between active (anagen) and quiescent (telogen) phases. The timing of hair cycles is advanced in prolactin receptor (PRLR) knockout mice, suggesting...
6.
Oakes S, Robertson F, Kench J, Gardiner-Garden M, Wand M, Green J, et al.
Oncogene
. 2006 Jul;
26(4):543-53.
PMID: 16862169
Top quartile serum prolactin levels confer a twofold increase in the relative risk of developing breast cancer. Prolactin exerts this effect at an ill defined point in the carcinogenic process,...
7.
Lindeman G, Wittlin S, Lada H, Naylor M, Santamaria M, Zhang J, et al.
Genes Dev
. 2001 Jul;
15(13):1631-6.
PMID: 11445538
Prolactin is essential for proliferation and differentiation of the developing mammary gland. We have explored a role for Suppressor of Cytokine Signaling 1 (SOCS1) as a modulator of the prolactin...
8.
Craven A, Ormandy C, Robertson F, Wilkins R, Kelly P, Nixon A, et al.
Endocrinology
. 2001 May;
142(6):2533-9.
PMID: 11356702
Pituitary PRL regulates seasonal hair follicle growth cycles in many mammals. Here we present the first evidence implicating PRL in the nonseasonal, wave-like pelage replacement of laboratory mice. In this...
9.
McClellan K, Robertson F, Kindblom J, Wennbo H, Tornell J, Bouchard B, et al.
Invest Ophthalmol Vis Sci
. 2001 Jan;
42(1):23-30.
PMID: 11133844
Purpose: To determine whether prolactin receptor is essential for normal development and function of the lacrimal gland and whether hyperprolactinemia can alter lacrimal development. Methods: Lacrimal gland morphology and function...
10.
Binart N, Ormandy C, Kelly P
Adv Exp Med Biol
. 2000 Aug;
480:85-92.
PMID: 10959413
Prolactin (PRL), synthesized by the anterior pituitary and to a lesser extent by numerous extrapituitary tissues, affects more physiological processes than all other pituitary hormones combined. This hormone is involved...