C F Dewey Jr
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Explore the profile of C F Dewey Jr including associated specialties, affiliations and a list of published articles.
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28
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1515
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Recent Articles
1.
Bindschadler M, Osborn E, Dewey Jr C, McGrath J
Biophys J
. 2004 Apr;
86(5):2720-39.
PMID: 15111391
We have derived a broad, deterministic model of the steady-state actin cycle that includes its major regulatory mechanisms. Ours is the first model to solve the complete nucleotide profile within...
2.
Dao N, McCormick P, Dewey Jr C
Ann Biomed Eng
. 2001 Jan;
28(8):1032-42.
PMID: 11144665
Modern biology is rapidly laying the foundation necessary for integrated modeling of physiological processes in living organisms. The human physiome project attempts to model interactions between biochemicals, cellular organelles, cells,...
3.
McGrath J, Osborn E, Tardy Y, Dewey Jr C, Hartwig J
Proc Natl Acad Sci U S A
. 2000 May;
97(12):6532-7.
PMID: 10823888
Cycling of actin subunits between monomeric and filamentous phases is essential for cell crawling behavior. We investigated actin filament turnover rates, length, number, barbed end exposure, and binding of cofilin...
4.
Cheng Y, Hartemink C, Hartwig J, Dewey Jr C
J Biomech
. 1999 Dec;
33(1):105-13.
PMID: 10609523
In eucaryotic cells, actin filaments are abundant components in the cytoskeleton where they form a complex three dimensional (3D) structural network that provides the cell with its shape and mechanical...
5.
Nagel T, RESNICK N, Dewey Jr C, Gimbrone Jr M
Arterioscler Thromb Vasc Biol
. 1999 Aug;
19(8):1825-34.
PMID: 10446060
The vascular endothelium is exposed to a spectrum of fluid mechanical forces generated by blood flow; some of these, such as fluid shear stress, can directly modulate endothelial gene expression....
6.
McGrath J, Hartwig J, Tardy Y, Dewey Jr C
Microsc Res Tech
. 1998 Dec;
43(5):385-94.
PMID: 9858336
Cytoplasmic actin distributes between monomeric and filamentous phases in cells. As cells crawl, actin polymerizes near the plasma membrane of expanding peripheral cytoplasm and depolymerizes elsewhere. Thus, the finite actin...
7.
McGrath J, Tardy Y, Dewey Jr C, Meister J, Hartwig J
Biophys J
. 1998 Sep;
75(4):2070-8.
PMID: 9746549
The analogous techniques of photoactivation of fluorescence (PAF) and fluorescence recovery after photobleaching (FRAP) have been applied previously to the study of actin dynamics in living cells. Traditionally, separate experiments...
8.
Satcher R, Dewey Jr C, Hartwig J
Microcirculation
. 1998 Feb;
4(4):439-53.
PMID: 9431512
Objective: The mechanism by which cultured endothelial cells respond to shear stress is controversial. The cell surface and cytoskeleton are involved, but their roles are undefined. In this study, previously...
9.
Tardy Y, RESNICK N, Nagel T, Gimbrone Jr M, Dewey Jr C
Arterioscler Thromb Vasc Biol
. 1997 Dec;
17(11):3102-6.
PMID: 9409299
Wall shear stress has been implicated in the genesis of atherosclerosis because a strong correlation exists between the location of developing arterial lesions and regions where particular gradients in stress...
10.
Dewey Jr C, Thomas J, Kunt M, Hunter I
Telemed J
. 1996 Jul;
2(2):87-100.
PMID: 10165360
Ultrasound imaging is currently used as a primary diagnostic tool in cardiology, abdominal disorders, pulmonary medicine, trauma, and obstetrics. Because of its relatively low capital and operating costs as well...