C E Cass
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Explore the profile of C E Cass including associated specialties, affiliations and a list of published articles.
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Articles
119
Citations
2220
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Recent Articles
1.
Hillgren K, Keppler D, Zur A, Giacomini K, Stieger B, Cass C, et al.
Clin Pharmacol Ther
. 2013 Apr;
94(1):52-63.
PMID: 23588305
The International Transporter Consortium (ITC) has recently described seven transporters of particular relevance to drug development. Based on the second ITC transporter workshop in 2012, we have identified additional transporters...
2.
Young J, Yao S, Sun L, Cass C, Baldwin S
Xenobiotica
. 2008 Aug;
38(7-8):995-1021.
PMID: 18668437
1. The human (h) SLC29 family of integral membrane proteins is represented by four members, designated equilibrative nucleoside transporters (ENTs) because of the properties of the first-characterized family member, hENT1....
3.
Mackey J, Baldwin S, Young J, Cass C
Drug Resist Updat
. 2006 Nov;
1(5):310-24.
PMID: 17092812
This article discusses the role of nucleoside transport processes in the cytotoxicity of clinically important anticancer nucleosides. This article summarizes recent advances in the molecular biology of nucleoside transport proteins,...
4.
Mani R, Usova E, Eriksson S, Cass C
Nucleosides Nucleotides Nucleic Acids
. 2004 Dec;
23(8-9):1343-6.
PMID: 15571255
Deoxycytidine kinase (dCK), is responsible for the phosphorylation of deoxynucleosides to the corresponding monophosphates using ATP or UTP as phosphate donors. Steady-state intrinsic fluorescence measurements were used to study interaction...
5.
Szkotak A, Ng A, Man S, Baldwin S, Cass C, Young J, et al.
J Membr Biol
. 2003 Jun;
192(3):169-79.
PMID: 12820662
The purpose of this study was to characterize the role of adenosine-dependent regulation of anion secretion in Calu-3 cells. RT-PCR studies showed that Calu-3 cells expressed mRNA for A2A and...
6.
Reiman T, Graham K, Wong J, Belch A, Coupland R, Young J, et al.
Leukemia
. 2002 Aug;
16(9):1886-7.
PMID: 12200718
No abstract available.
7.
Musa H, Dobrzynski H, Berry Z, Abidi F, Cass C, Young J, et al.
J Histochem Cytochem
. 2002 Feb;
50(3):305-9.
PMID: 11850433
Adenosine exerts multiple receptor-mediated effects in the heart, including a negative chronotropic effect on the sinoatrial node. The aim of this study was to investigate the distribution of the equilibrative...
8.
Szkotak A, Ng A, Sawicka J, Baldwin S, Man S, Cass C, et al.
Am J Physiol Cell Physiol
. 2001 Nov;
281(6):C1991-2002.
PMID: 11698258
The regulatory actions of adenosine on ion channel function are mediated by four distinct membrane receptors. The concentration of adenosine in the vicinity of these receptors is controlled, in part,...
9.
Sinclair C, Powell A, Xiong W, LaRiviere C, Baldwin S, Cass C, et al.
Br J Pharmacol
. 2001 Oct;
134(5):1037-44.
PMID: 11682452
1. Adenosine kinase (AK) inhibitors can enhance adenosine levels and potentiate adenosine receptor activation. As the AK inhibitors 5' iodotubercidin (ITU) and 5-amino-5'-deoxyadenosine (NH(2)dAdo) are nucleoside analogues, we hypothesized that...
10.
Mani R, Karimi-Busheri F, Cass C, Weinfeld M
Biochemistry
. 2001 Oct;
40(43):12967-73.
PMID: 11669634
Human polynucleotide kinase (hPNK) is a putative DNA repair enzyme in the base excision repair pathway required for processing and rejoining strand-break termini. This study represents the first systematic examination...