C C Malbon
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Explore the profile of C C Malbon including associated specialties, affiliations and a list of published articles.
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168
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2438
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Recent Articles
11.
Liu T, DeCostanzo A, Liu X, Wang Hy , Hallagan S, Moon R, et al.
Science
. 2001 Jun;
292(5522):1718-22.
PMID: 11387477
The frizzled receptors, which mediate development and display seven hydrophobic, membrane-spanning segments, are cell membrane-localized. We constructed a chimeric receptor with the ligand-binding and transmembrane segments from the beta2-adrenergic receptor...
12.
Fan G, Shumay E, Wang H, Malbon C
J Biol Chem
. 2001 Apr;
276(26):24005-14.
PMID: 11309381
The cyclic AMP-dependent kinase-anchoring proteins (AKAPs) function as scaffolds for a wide-range of protein-protein interactions. The 250-kDa AKAP known as gravin plays a central role in organizing G-protein-coupled receptors to...
13.
Fan G, Shumay E, Malbon C, Wang H
J Biol Chem
. 2001 Mar;
276(16):13240-7.
PMID: 11278940
The nonreceptor tyrosine kinase Src has been implicated in the switching of signaling of beta2-adrenergic receptors from adenylylcyclase coupling to the mitogen-activated protein kinase pathway. In the current work, we...
14.
Doronin S, Lin F, Wang H, Malbon C
Protein Expr Purif
. 2000 Nov;
20(3):451-61.
PMID: 11087685
The ability of the cytoplasmic, full-length C-terminus of the beta 2-adrenergic receptor (BAC1) expressed in Escherichia coli to act as a functional domain and substrate for protein phosphorylation was tested....
15.
Wang H, Doronin S, Malbon C
J Biol Chem
. 2000 Aug;
275(46):36086-93.
PMID: 10940302
Insulin activates a complex set of intracellular responses, including the activation of mitogen-activated protein kinases Erk1,2. The counterregulatory actions of insulin on catecholamine action are well known and include phosphorylation...
16.
Lin F, Wang H, Malbon C
J Biol Chem
. 2000 Jun;
275(25):19025-34.
PMID: 10858453
Agonist-induced desensitization and resensitization of G-protein-linked receptors involve the interaction of receptors with protein kinases, phosphatases, beta-arrestin, and clathrin organized by at least one scaffold protein. The dynamic composition of...
17.
Kanungo J, Potapova I, Malbon C, Wang H
J Biol Chem
. 2000 May;
275(31):24032-9.
PMID: 10807916
Differentiation of P19 embryonal carcinoma cells in response to the morphogen retinoic acid is regulated by Galpha(12/13) and is associated with activation of c-Jun N-terminal kinase. The role of MEKK1...
18.
Kuhl M, Sheldahl L, Malbon C, Moon R
J Biol Chem
. 2000 Apr;
275(17):12701-11.
PMID: 10777564
Wnt ligands working through Frizzled receptors have a differential ability to stimulate release of intracellular calcium (Ca(2+)) and activation of protein kinase C (PKC). Since targets of this Ca(2+) release...
19.
Wang H, Lin F, Malbon C
Methods Mol Biol
. 2000 Feb;
126:241-58.
PMID: 10685416
No abstract available.
20.
Liu X, Liu T, Slusarski D, Malbon C, Moon R, Wang H
Proc Natl Acad Sci U S A
. 1999 Dec;
96(25):14383-8.
PMID: 10588714
The frizzled gene family of putative Wnt receptors encodes proteins that have a seven-transmembrane-spanning motif characteristic of G protein-linked receptors, though no loss-of-function studies have demonstrated a requirement for G...