C A Blizzard
Overview
Explore the profile of C A Blizzard including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
56
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0
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Recent Articles
1.
Clark J, Chuckowree J, Dyer M, Dickson T, Blizzard C
Sci Rep
. 2020 Jan;
10(1):918.
PMID: 31969604
Brain penetrant microtubule stabilising agents (MSAs) are being increasingly validated as potential therapeutic strategies for neurodegenerative diseases and traumatic injuries of the nervous system. MSAs are historically used to treat...
2.
Clark J, Blizzard C, Breslin M, Yeaman E, Lee K, Chuckowree J, et al.
Neuropathol Appl Neurobiol
. 2018 Jan;
44(6):590-605.
PMID: 29380402
Aims: Degeneration of the distal neuromuscular circuitry is a hallmark pathology of Amyotrophic Lateral Sclerosis (ALS). The potential for microtubule dysfunction to be a critical pathophysiological mechanism in the destruction...
3.
King A, Dickson T, Blizzard C, Woodhouse A, Foster S, Chung R, et al.
Neurobiol Aging
. 2009 May;
32(3):459-69.
PMID: 19427060
Amyotrophic lateral sclerosis (ALS) is a devastating disorder involving loss of movement due to degeneration of motor neurons. Studies suggest that in ALS axonal dysfunction precedes the death of motor...
4.
King A, Dickson T, Blizzard C, Foster S, Chung R, West A, et al.
Eur J Neurosci
. 2007 Oct;
26(8):2151-9.
PMID: 17908171
Excitotoxicity has been implicated as a potential cause of neuronal degeneration in amyotrophic lateral sclerosis (ALS). It has not been clear how excitotoxic injury leads to the hallmark pathological changes...
5.
Blizzard C, Haas M, Vickers J, Dickson T
Eur J Neurosci
. 2007 Sep;
26(5):1100-8.
PMID: 17767489
While long-distance regeneration may be limited in mammalian species, it is becoming apparent that damaged mature neurons retain some capacity for attempted regeneration and that the adult CNS is not...