Bryan Kestenbaum
Overview
Explore the profile of Bryan Kestenbaum including associated specialties, affiliations and a list of published articles.
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215
Citations
8659
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Recent Articles
1.
Granda M, Luitweiler E, Prince D, Allegretti A, Paine C, Pichler R, et al.
Clin Transl Gastroenterol
. 2024 Oct;
15(11):e00775.
PMID: 39374041
Introduction: Cirrhosis affects all structures of the kidney, in particular the tubules, which are responsible for secretion of protein-bound metabolites and electrolyte/water homeostasis. Yet, prevailing assessments of kidney function focus...
2.
Vlasschaert C, Pan Y, Chen J, Akwo E, Rao V, Hixson J, et al.
medRxiv
. 2024 Jul;
PMID: 38946975
Background: Clonal hematopoiesis of indeterminate potential (CHIP) is a common inflammatory condition of aging that causes myriad end-organ damage. We have recently shown associations for CHIP with acute kidney injury...
3.
Granda M, Tian F, Zelnick L, Bhatraju P, Hallowell J, Wurfel M, et al.
Crit Care Explor
. 2024 Jun;
6(7):e1109.
PMID: 38922318
Importance: COVID-19 may injure the kidney tubules via activation of inflammatory host responses and/or direct viral infiltration. Most studies of kidney injury in COVID-19 lacked contemporaneous controls or measured kidney...
4.
Barzilay J, Buzkova P, Bielinski S, Cotch M, Kestenbaum B, Austin T, et al.
Osteoporos Int
. 2024 Jun;
35(9):1595-1604.
PMID: 38913124
Purpose: Microvascular diseases of the eye, kidney, and brain are associated with endothelial dysfunction and increased hip fracture risk. To explore the basis for higher hip fracture risk, we comprehensively...
5.
Granda M, Tian F, Zelnick L, Bhatraju P, Wurfel M, Hoofnagle A, et al.
Res Sq
. 2024 Mar;
PMID: 38464257
Background: Coronavirus disease-2019 (COVID-19) may injure the kidney tubules via activation of inflammatory host responses and/or direct viral infiltration. Most studies of kidney injury in COVID-19 lacked contemporaneous controls or...
6.
Vlasschaert C, Robinson-Cohen C, Chen J, Akwo E, Parker A, Silver S, et al.
Nat Med
. 2024 Mar;
30(3):810-817.
PMID: 38454125
Age is a predominant risk factor for acute kidney injury (AKI), yet the biological mechanisms underlying this risk are largely unknown. Clonal hematopoiesis of indeterminate potential (CHIP) confers increased risk...
7.
McKinzie S, Kaverina N, Schweickart R, Chaney C, Eng D, Pereira B, et al.
Am J Physiol Renal Physiol
. 2024 Feb;
326(4):F644-F660.
PMID: 38420674
Patients with hypertension or obesity can develop glomerular dysfunction characterized by injury and depletion of podocytes. To better understand the molecular processes involved, young mice were treated with either deoxycorticosterone...
8.
Granda M, Huang W, Yeung C, Isoherranen N, Kestenbaum B
Clin Transl Sci
. 2023 Nov;
17(1):e13678.
PMID: 37921258
Kidney function-adjusted drug dosing is currently based solely on the estimated glomerular filtration rate (GFR), however, kidney drug handling is accomplished by a combination of filtration, tubular secretion, and re-absorption....
9.
Sharma K, Zhang G, Hansen J, Bjornstad P, Lee H, Menon R, et al.
J Clin Invest
. 2023 Aug;
133(20).
PMID: 37616058
Diabetic kidney disease (DKD) can lead to end-stage kidney disease (ESKD) and mortality; however, few mechanistic biomarkers are available for high-risk patients, especially those without macroalbuminuria. Urine from participants with...
10.
Sharma K, Zhang G, Hansen J, Bjornstad P, Lee H, Menon R, et al.
medRxiv
. 2023 Jul;
PMID: 37398187
Diabetic kidney disease (DKD) can lead to end-stage kidney disease (ESKD) and mortality, however, few mechanistic biomarkers are available for high risk patients, especially those without macroalbuminuria. Urine from participants...