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Brian W Parks

Explore the profile of Brian W Parks including associated specialties, affiliations and a list of published articles. Areas
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Articles 41
Citations 1999
Followers 0
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Recent Articles
1.
Votava J, Fan J, Parks B
PLoS One . 2024 Dec; 19(12):e0315719. PMID: 39666708
The lactating mammary gland strongly induces de novo lipogenesis (DNL) to support the synthesis of fatty acids, triglycerides, and cholesterol found within milk. In monogastric species, glucose is a major...
2.
Michorowska S, Vogel K, Jain R, Clair S, Simcox J, Parks B
Biochem Biophys Res Commun . 2024 Nov; 741:151059. PMID: 39608054
Agpat5 (1-acylglycerol-3-phosphate O-acyltransferase 5) is a broadly expressed lipid regulatory enzyme involved in glycerophospholipid metabolism. Multiple genetic studies in mice and humans have identified that Agpat5 is associated with plasma...
3.
Votava J, John S, Li Z, Chen S, Fan J, Parks B
J Lipid Res . 2024 Feb; 65(3):100525. PMID: 38417553
The availability of genome-wide transcriptomic and proteomic datasets is ever-increasing and often not used beyond initial publication. Here, we applied module-based coexpression network analysis to a comprehensive catalog of 35 ...
4.
Price T, Stapleton D, Schueler K, Norris M, Parks B, Yandell B, et al.
PLoS Genet . 2023 Jul; 19(7):e1010713. PMID: 37523383
We and others have previously shown that genetic association can be used to make causal connections between gene loci and small molecules measured by mass spectrometry in the bloodstream and...
5.
Price T, Stapleton D, Schueler K, Norris M, Parks B, Yandell B, et al.
bioRxiv . 2023 Mar; PMID: 36993241
We and others have previously shown that genetic association can be used to make causal connections between gene loci and small molecules measured by mass spectrometry in the bloodstream and...
6.
Kasza I, Cuncannan C, Michaud J, Nelson D, Yen C, Jain R, et al.
Biochimie . 2022 Nov; 210:82-98. PMID: 36372307
Thermoneutral housing has been shown to promote more accurate and robust development of several pathologies in mice. Raising animal housing temperatures a few degrees may create a relatively straightforward opportunity...
7.
Xu H, Thomas M, Kaul S, Kallinger R, Ouweneel A, Maruko E, et al.
Arterioscler Thromb Vasc Biol . 2021 Sep; 41(11):2708-2725. PMID: 34551590
Objective: To investigate the role of adipocyte Pcpe2 (procollagen C-endopeptidase enhancer 2) in SR-BI (scavenger receptor class BI)-mediated HDL-C (high-density lipoprotein cholesterol) uptake and contributions to adipose lipid storage. Approach...
8.
Votava J, Parks B
Curr Opin Lipidol . 2021 Mar; 32(2):141-146. PMID: 33651746
Purpose Of Review: More than one hundred loci have been identified from human genome-wide association studies (GWAS) for blood lipids. Despite the success of GWAS in identifying loci, subsequent prioritization...
9.
Norheim F, Chella Krishnan K, Bjellaas T, Vergnes L, Pan C, Parks B, et al.
Mol Syst Biol . 2021 Jan; 17(1):e9684. PMID: 33417276
To elucidate the contributions of specific lipid species to metabolic traits, we integrated global hepatic lipid data with other omics measures and genetic data from a cohort of about 100...
10.
Tuominen I, Fuqua B, Pan C, Renaud N, Wroblewski K, Civelek M, et al.
Cell Mol Gastroenterol Hepatol . 2020 Sep; 11(1):199-220. PMID: 32866618
Background & Aims: Liver fibrosis is a multifactorial trait that develops in response to chronic liver injury. Our aim was to characterize the genetic architecture of carbon tetrachloride (CCl)-induced liver...