Brian P McCarthy
Overview
Explore the profile of Brian P McCarthy including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
399
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0
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Recent Articles
1.
Onos K, Quinney S, Jones D, Masters A, Pandey R, Keezer K, et al.
Alzheimers Dement (N Y)
. 2022 Aug;
8(1):e12329.
PMID: 36016830
Introduction: Hyperexcitability and epileptiform activity are commonplace in Alzheimer's disease (AD) patients and associated with impaired cognitive function. The anti-seizure drug levetiracetam (LEV) is currently being evaluated in clinical trials...
2.
Brandt S, Wang S, Dejani N, Klopfenstein N, Winfree S, Filgueiras L, et al.
JCI Insight
. 2018 Sep;
3(17).
PMID: 30185672
Poorly controlled diabetes leads to comorbidities and enhanced susceptibility to infections. While the immune components involved in wound healing in diabetes have been studied, the components involved in susceptibility to...
3.
Brandt S, Klopfenstein N, Wang S, Winfree S, McCarthy B, Territo P, et al.
PLoS Pathog
. 2018 Aug;
14(8):e1007244.
PMID: 30102746
The early events that shape the innate immune response to restrain pathogens during skin infections remain elusive. Methicillin-resistant Staphylococcus aureus (MRSA) infection engages phagocyte chemotaxis, abscess formation, and microbial clearance....
4.
Adelaiye-Ogala R, Budka J, Damayanti N, Arrington J, Ferris M, Hsu C, et al.
Cancer Res
. 2017 Oct;
77(23):6651-6666.
PMID: 28978636
Acquired and intrinsic resistance to receptor tyrosine kinase inhibitors (RTKi) represents a major hurdle in improving the management of clear cell renal cell carcinoma (ccRCC). Recent reports suggest that drug...
5.
Allen M, McNerny E, Aref M, Organ J, Newman C, McGowan B, et al.
PLoS One
. 2017 Aug;
12(8):e0181750.
PMID: 28793321
A growing number of studies have investigated combination treatment as an approach to treat bone disease. The goal of this study was to investigate the combination of alendronate and raloxifene...
6.
Neto-Neves E, Brown M, Zaretskaia M, Rezania S, Goodwill A, McCarthy B, et al.
Am J Pathol
. 2017 Feb;
187(4):700-712.
PMID: 28183533
Our understanding of the pathophysiological basis of chronic thromboembolic pulmonary hypertension (CTEPH) will be accelerated by an animal model that replicates the phenotype of human CTEPH. Sprague-Dawley rats were administered...
7.
Territo P, Riley A, McCarthy B, Hutchins G
EJNMMI Phys
. 2016 Oct;
3(1):24.
PMID: 27766592
Recent advancements in PET instrumentation have made the non-invasive assessment of cardiovascular function in small animals a reality. The majority of small animal PET systems use stationary detector gantries, thus...
8.
Territo P, Meyer J, Peters J, Riley A, McCarthy B, Gao M, et al.
J Nucl Med
. 2016 Oct;
58(3):458-465.
PMID: 27765863
The purinergic receptor subtype 7 (P2X7R) represents a novel molecular target for imaging neuroinflammation via PET. GSK1482160, a potent P2X7R antagonist, has high receptor affinity, high blood-brain barrier penetration, and...
9.
Hato T, Friedman A, Mang H, Plotkin Z, Dube S, Hutchins G, et al.
Am J Physiol Renal Physiol
. 2016 Jan;
310(8):F717-F725.
PMID: 26764206
The metabolic status of the kidney is a determinant of injury susceptibility and a measure of progression for many disease processes; however, noninvasive modalities to assess kidney metabolism are lacking....
10.
Territo P, Maluccio M, Riley A, McCarthy B, Fletcher J, Tann M, et al.
BMC Med Imaging
. 2015 May;
15:15.
PMID: 25981587
Background: Hepatocellular carcinoma (HCC) remains a global health problem with unique diagnostic and therapeutic challenges, including difficulties in identifying the highest risk patients. Previous work from our lab has established...