Brian G Condie
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Explore the profile of Brian G Condie including associated specialties, affiliations and a list of published articles.
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28
Citations
953
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Recent Articles
1.
Ma Z, Kang S, Condie B, Manley N
Development
. 2024 Jul;
151(14).
PMID: 38958026
Thymic epithelial cells (TECs) are crucial to the ability of the thymus to generate T cells for the adaptive immune system in vertebrates. However, no in vitro system for studying...
2.
Li J, Wachsmuth L, Xiao S, Condie B, Manley N
Development
. 2023 Mar;
150(8).
PMID: 36975725
The transcription factor FOXN1 is essential for fetal thymic epithelial cell (TEC) differentiation and proliferation. Postnatally, Foxn1 levels vary widely between TEC subsets, from low/undetectable in putative TEC progenitors to...
3.
Peissig K, Condie B, Manley N
Endocrinol Metab Clin North Am
. 2018 Nov;
47(4):733-742.
PMID: 30390809
The parathyroid glands are essential for regulating calcium homeostasis in the body. The genetic programs that control parathyroid fate specification, morphogenesis, differentiation, and survival are only beginning to be delineated,...
4.
Condie B
Genesis
. 2016 Apr;
54(5):245-56.
PMID: 27074373
Gene Expression Nervous System Atlas (GENSAT) transgenic mice express EGFP, tdTomato, or Cre recombinase in a wide range of cell types. The mice and the bacterial artificial chromosome transgenes are...
5.
Condie B, Urbanski W
Methods Mol Biol
. 2013 Dec;
1092:395-403.
PMID: 24318832
Effective tools for searching the biomedical literature are essential for identifying reagents or mouse strains as well as for effective experimental design and informed interpretation of experimental results. We have...
6.
Casoni F, Hutchins B, Donohue D, Fornaro M, Condie B, Wray S
J Cell Sci
. 2012 Sep;
125(Pt 21):5015-25.
PMID: 22976302
Stromal derived growth factor (SDF-1) and gamma-aminobutyric acid (GABA) are two extracellular cues that regulate the rate of neuronal migration during development and may act synergistically. The molecular mechanisms of...
7.
Wei Q, Condie B
PLoS One
. 2011 Nov;
6(11):e26795.
PMID: 22087235
Background: Thymic epithelial cells (TECs) are necessary for normal T cell development. Currently, one transcription factor, Foxn1 is known to be necessary for the progression of fetal TEC differentiation. However,...
8.
Wei Q, Manley N, Condie B
J Vis Exp
. 2011 Oct;
(56).
PMID: 22005971
Whole mount in situ hybridization is a very informative approach for defining gene expression patterns in embryos. The in situ hybridization procedures are lengthy and technically demanding with multiple important...
9.
Guo T, Mandai K, Condie B, Wickramasinghe S, Capecchi M, Ginty D
Nat Neurosci
. 2010 Dec;
14(1):31-6.
PMID: 21151121
Species are endowed with unique sensory capabilities that are encoded by divergent neural circuits. One potential explanation for how divergent circuits have evolved is that conserved extrinsic signals are differentially...
10.
Manley N, Condie B
Prog Mol Biol Transl Sci
. 2010 Aug;
92:103-20.
PMID: 20800818
Transcriptional regulatory networks are the central regulatory mechanisms that control organ identity, patterning, and differentiation. In the case of the thymus, several key transcription factors have been identified that are...