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Brian Bostick

Explore the profile of Brian Bostick including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Sowers J, Habibi J, Jia G, Bostick B, Manrique-Acevedo C, Lastra G, et al.
Metabolism . 2020 Apr; 109:154223. PMID: 32275972
Objective: Obesity is associated with myocardial fibrosis and impaired diastolic relaxation, abnormalities that are especially prevalent in women. Normal coronary vascular endothelial function is integral in mediating diastolic relaxation, and...
2.
Ghosh A, Yue Y, Long C, Bostick B, Duan D
Mol Ther . 2017 Feb; 15(6):1220. PMID: 28182924
No abstract available.
3.
Bostick B, Aroor A, Habibi J, Durante W, Ma L, Demarco V, et al.
Metabolism . 2016 Dec; 66:14-22. PMID: 27923445
Objective: Obesity is a global epidemic with profound cardiovascular disease (CVD) complications. Obese women are particularly vulnerable to CVD, suffering higher rates of CVD compared to non-obese females. Diastolic dysfunction...
4.
Padilla J, Ramirez-Perez F, Habibi J, Bostick B, Aroor A, Hayden M, et al.
Hypertension . 2016 Aug; 68(5):1236-1244. PMID: 27572153
We recently showed that Western diet-induced obesity and insulin resistance promotes endothelial cortical stiffness in young female mice. Herein, we tested the hypothesis that regular aerobic exercise would attenuate the...
5.
Yue Y, Wasala N, Bostick B, Duan D
Mol Ther Methods Clin Dev . 2016 Jul; 3:16045. PMID: 27419194
Dystrophin gene replacement holds the promise of treating Duchenne muscular dystrophy. Supraphysiological expression is a concern for all gene therapy studies. In the case of Duchenne muscular dystrophy, Chamberlain and...
6.
Bostick B, Habibi J, Demarco V, Jia G, Domeier T, Lambert M, et al.
Am J Physiol Heart Circ Physiol . 2015 Mar; 308(9):H1126-35. PMID: 25747754
Overnutrition/obesity predisposes individuals, particularly women, to diastolic dysfunction (DD), an independent predictor of future cardiovascular disease. We examined whether low-dose spironolactone (Sp) prevents DD associated with consumption of a Western...
7.
Bostick B, Whaley-Connell A
Semin Dial . 2014 Jul; 27(6):545-7. PMID: 24995999
No abstract available.
8.
Bostick B, Habibi J, Ma L, Aroor A, Rehmer N, Hayden M, et al.
Metabolism . 2014 Jun; 63(8):1000-11. PMID: 24933400
Objective: Consumption of a high-fat/high-fructose Western diet (WD) is linked to rising obesity and heart disease, particularly diastolic dysfunction which characterizes early obesity/metabolic cardiomyopathy. Mounting evidence supports a role for...
9.
Wasala N, Bostick B, Yue Y, Duan D
Hum Mol Genet . 2013 Mar; 22(13):2634-41. PMID: 23459935
Duchenne muscular dystrophy (DMD) is characterized by severe degeneration and necrosis of both skeletal and cardiac muscle. While many experimental therapies have shown great promise in treating skeletal muscle disease,...
10.
Bostick B, Shin J, Yue Y, Wasala N, Lai Y, Duan D
J Mol Cell Cardiol . 2012 May; 53(2):217-22. PMID: 22587991
Duchenne muscular dystrophy (DMD) is a fatal genetic disease caused by the absence of the sarcolemmal protein dystrophin. Dilated cardiomyopathy leading to heart failure is a significant source of morbidity...