Bret M Evers
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Explore the profile of Bret M Evers including associated specialties, affiliations and a list of published articles.
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53
Citations
721
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Recent Articles
1.
Casey A, Stewart N, Zaidi N, Gray H, Fields H, Sakurai M, et al.
Mol Metab
. 2025 Mar;
:102120.
PMID: 40073934
The bi-functional enzyme FicD catalyzes AMPylation and deAMPylation of the endoplasmic reticulum chaperone BiP to modulate ER homeostasis and the unfolded protein response (UPR). Human hFicD with an arginine-to-serine mutation...
2.
Calvier L, Wasser C, Solow E, Wu S, Evers B, Karp D, et al.
Proc Natl Acad Sci U S A
. 2025 Mar;
122(11):e2418642122.
PMID: 40073057
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation, pannus formation, and progressive joint destruction. The inflammatory milieu in RA drives endothelial cell activation and upregulation of...
3.
Cai L, Hammond N, Tasdogan A, Alsamraae M, Yang C, Cameron R, et al.
Cancer Discov
. 2025 Feb;
:OF1-OF15.
PMID: 39960461
Intraoperative 13C-glucose infusions in patients with NSCLC show that tumors with high labeling of TCA cycle intermediates progress rapidly, resulting in metastasis and early death. Blocking this pathway suppresses metastasis...
4.
Thomas-Jardin S, Suresh S, Arce A, Novaresi N, Stein E, Thomas L, et al.
bioRxiv
. 2024 Nov;
PMID: 39554171
Statement Of Significance: This study uncovers a novel mechanism for the coordinated translational regulation of the PD-L1/PD1 and CD155/TIGIT immune checkpoint pathways and highlights the ISR as a therapeutic vulnerability...
5.
Casey A, Stewart N, Zaidi N, Gray H, Fields H, Sakurai M, et al.
bioRxiv
. 2024 Nov;
PMID: 39484587
Bi-functional enzyme FicD regulates the endoplasmic reticulum chaperone BiP using AMPylation and deAMPylation during ER homeostasis and stress, respectively. Human FicD with an arginine-to-serine mutation disrupts FicD deAMPylation activity resulting...
6.
Somawardana I, Prasad B, Kay W, Hunt C, Adams J, Kawaguchi B, et al.
J Infect
. 2024 Sep;
89(5):106271.
PMID: 39278276
Objectives: We aimed to evaluate the effectiveness of alternating magnetic fields (AMF) combined with antibiotics in reducing Staphylococcus aureus biofilm on metal implants in a large animal model, compared to...
7.
Pottier C, Kucukali F, Baker M, Batzler A, Jenkins G, van Blitterswijk M, et al.
medRxiv
. 2024 Jul;
PMID: 38978643
Frontotemporal lobar degeneration with neuronal inclusions of the TAR DNA-binding protein 43 (FTLD-TDP) is a fatal neurodegenerative disorder with only a limited number of risk loci identified. We report our...
8.
Yu J, Guo T, Gupta A, Llano E, Wajahat N, Slater S, et al.
bioRxiv
. 2024 Jul;
PMID: 38948776
Cachexia is a wasting syndrome comprised of adipose, muscle, and weight loss observed in cancer patients. Tumor loss-of-function mutations in , a regulator of the energy sensor AMP-activated protein kinase,...
9.
Dobariya A, El Ahmadieh T, Good L, Hernandez-Reynoso A, Jakkamsetti V, Brown R, et al.
Sci Rep
. 2024 Apr;
14(1):9836.
PMID: 38684761
No abstract available.
10.
Mitra S, Chen B, Shelton J, Nitschke S, Wu J, Covington L, et al.
Acta Neuropathol
. 2024 Feb;
147(1):46.
PMID: 38411740
At least five enzymes including three E3 ubiquitin ligases are dedicated to glycogen's spherical structure. Absence of any reverts glycogen to a structure resembling amylopectin of the plant kingdom. This...