Brendan J McMorran
Overview
Explore the profile of Brendan J McMorran including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
596
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0
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Recent Articles
1.
Gare C, Palombi I, White A, Chavchich M, Edstein M, Lock A, et al.
ChemMedChem
. 2024 Oct;
20(2):e202400637.
PMID: 39379289
The devastating impact of malaria includes significant mortality and illness worldwide. Increasing resistance of the causative parasite, Plasmodium, to existing antimalarial drugs underscores a need for additional compounds with distinct...
2.
Lawrence N, Handley T, de Veer S, Harding M, Andraszek A, Hall L, et al.
ACS Infect Dis
. 2024 Aug;
10(8):2899-2912.
PMID: 39087267
The control of malaria, a disease caused by parasites that kills over half a million people every year, is threatened by the continual emergence and spread of drug resistance. Therefore,...
3.
Arunachalam V, Lea R, Hoy W, Lee S, Mott S, Savige J, et al.
Genome Med
. 2024 Feb;
16(1):29.
PMID: 38347632
Background: Chronic kidney disease (CKD) is highly prevalent among Indigenous Australians, especially those in remote regions. The Tiwi population has been isolated from mainland Australia for millennia and exhibits unique...
4.
Reis A, Rapadas M, Hammond J, Gamaarachchi H, Stevanovski I, Kumaheri M, et al.
Nature
. 2023 Dec;
624(7992):602-610.
PMID: 38093003
Indigenous Australians harbour rich and unique genomic diversity. However, Aboriginal and Torres Strait Islander ancestries are historically under-represented in genomics research and almost completely missing from reference datasets. Addressing this...
5.
Ningtyas D, Leitner F, Sohail H, Thong Y, Hicks S, Ali S, et al.
Blood
. 2023 Nov;
143(6):535-547.
PMID: 37992231
In humans, ∼0.1% to 0.3% of circulating red blood cells (RBCs) are present as platelet-RBC (P-RBC) complexes, and it is 1% to 2% in mice. Excessive P-RBC complexes are found...
6.
Samarasinghe S, Hoy W, Jadhao S, McMorran B, Guchelaar H, Nagaraj S
Front Pharmacol
. 2023 Jun;
14:1180640.
PMID: 37284308
Population genomic studies of individuals of Indigenous ancestry have been extremely limited comprising <0.5% of participants in international genetic databases and genome-wide association studies, contributing to a "genomic gap" that...
7.
Palombi I, Lawrence N, White A, Gare C, Craik D, McMorran B, et al.
Bioconjug Chem
. 2023 May;
34(6):1105-1113.
PMID: 37232456
Malaria continues to impose a global health burden. Drug-resistant parasites have emerged to each introduced small-molecule therapy, highlighting the need for novel treatment approaches for the future eradication of malaria....
8.
OConnor J, McNamara H, Cai Y, Coupland L, Gardiner E, Parish C, et al.
J Immunol
. 2022 Jun;
208(12):2738-2748.
PMID: 35649630
Liver-resident CD8 T cells can play critical roles in the control of pathogens, including and hepatitis B virus. Paradoxically, it has also been proposed that the liver may act as...
9.
Jadhao S, Hoy W, Lee S, Patel H, McMorran B, Flower R, et al.
Transfusion
. 2022 Apr;
62(5):1110-1120.
PMID: 35403234
Background: Red blood cell (RBC) membrane-associated blood group systems are clinically significant. Alloimmunisation is a persistent risk associated with blood transfusion owing to the antigen polymorphisms among these RBC-associated blood...
10.
Shankar A, Jadhao S, Hoy W, Foote S, Patel H, Scaria V, et al.
Pharmacogenomics J
. 2021 Nov;
22(2):100-108.
PMID: 34824386
Indigenous Australians face a disproportionately severe burden of chronic disease relative to other Australians, with elevated rates of morbidity and mortality. While genomics technologies are slowly gaining momentum in personalised...