Bradly G Wouters
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Explore the profile of Bradly G Wouters including associated specialties, affiliations and a list of published articles.
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139
Citations
10259
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Recent Articles
1.
Aynaud M, Caldwell L, Al-Zahrani K, Barutcu S, Chan K, Obersterescu A, et al.
Nat Commun
. 2024 Dec;
15(1):10795.
PMID: 39738001
Highly mutable pathogens generate viral diversity that impacts virulence, transmissibility, treatment, and thwarts acquired immunity. We previously described C19-SPAR-Seq, a high-throughput, next-generation sequencing platform to detect SARS-CoV-2 that we here...
2.
Lee S, Pyo A, Mohammadi H, Zhang J, Dvorkin-Gheva A, Malbeteau L, et al.
Sci Adv
. 2024 Oct;
10(40):eadq0355.
PMID: 39356760
2-Aminoethanethiol dioxygenase (ADO) is a thiol dioxygenase that sulfinylates cysteamine and amino-terminal cysteines in polypeptides. The pathophysiological roles of ADO remain largely unknown. Here, we demonstrate that ADO expression represents...
3.
Alexander M, Zaidi M, Larson N, Mullan A, Pavelko K, Stegall M, et al.
Am J Transplant
. 2023 Nov;
24(4):549-563.
PMID: 37979921
Kidney allograft inflammation, mostly attributed to rejection and infection, is an important cause of graft injury and loss. Standard histopathological assessment of allograft inflammation provides limited insights into biological processes...
4.
Huang L, Vellanki R, Zhu Z, Wouters B, Keshavjee S, Liu M
Int J Mol Sci
. 2023 Sep;
24(17).
PMID: 37685927
Ex vivo lung perfusion (EVLP) has increased donor lung utilization through assessment of "marginal" lungs prior to transplantation. To develop it as a donor lung reconditioning platform, prolonged EVLP is...
5.
Kondratyev M, Pesic A, Ketela T, Stickle N, Beswick C, Shalev Z, et al.
Commun Biol
. 2023 May;
6(1):538.
PMID: 37202533
During cancer development, tumor cells acquire changes that enable them to invade surrounding tissues and seed metastasis at distant sites. These changes contribute to the aggressiveness of metastatic cancer and...
6.
Marastoni S, Madariaga A, Pesic A, Nair S, Li Z, Shalev Z, et al.
Cancer Res Commun
. 2023 Mar;
2(5):293-306.
PMID: 36875717
Significance: The combination of the antifungal drug itraconazole with antimalarial drug hydroxychloroquine leads to a cytotoxic lysosomal dysfunction, supporting the rational for further research on lysosomal targeting in ovarian cancer.
7.
Jamieson S, Tsai P, Kondratyev M, Budhani P, Liu A, Senzer N, et al.
JCI Insight
. 2023 Feb;
8(4).
PMID: 36810255
No abstract available.
8.
Mlecnik B, Lugli A, Bindea G, Marliot F, Bifulco C, Lee J, et al.
Cancers (Basel)
. 2023 Jan;
15(2).
PMID: 36672367
Background: The prognostic value of Immunoscore was evaluated in Stage II/III colon cancer (CC) patients, but it remains unclear in Stage I/II, and in early-stage subgroups at risk. An international...
9.
Huang L, Hough O, Vellanki R, Takahashi M, Zhu Z, Xiang Y, et al.
J Heart Lung Transplant
. 2022 Nov;
42(2):183-195.
PMID: 36411189
Background: The clinical application of normothermic ex vivo lung perfusion (EVLP) has increased donor lung utilization for transplantation through functional assessment. To develop it as a platform for donor lung...
10.
Cadavid J, Latour S, Nowlan F, Co I, Landon-Brace N, Wouters B, et al.
Adv Healthc Mater
. 2022 Oct;
12(14):e2201846.
PMID: 36308030
The spatial configuration of cells in the tumor microenvironment (TME) affects both cancer and fibroblast cell phenotypes contributing to the clinical challenge of tumor heterogeneity and therapeutic resistance. This is...