Bradley L Pentelute
Overview
Explore the profile of Bradley L Pentelute including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
136
Citations
3037
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Yesilcimen A, Gandhesiri S, Travaline T, Callahan A, Tokareva O, Loas A, et al.
J Org Chem
. 2025 Feb;
90(9):3365-3372.
PMID: 40008609
The chemical synthesis of proteins (CSP) has been an essential tool in studying and understanding the role of these biological polymers and in enabling the discovery of novel classes of...
2.
Brown J, Lee M, Vuong W, Loas A, Pentelute B
Anal Chem
. 2025 Feb;
97(7):3855-3863.
PMID: 39949296
Affinity selection-mass spectrometry (AS-MS) is a ligand discovery platform that relies upon mass spectrometry to identify molecules bound to a biomolecular target. When utilized with large peptide libraries (10 members),...
3.
Fittolani G, Kutateladze D, Loas A, Buchwald S, Pentelute B
J Am Chem Soc
. 2025 Jan;
147(5):4188-4197.
PMID: 39840443
The remarkable efficiency with which enzymes catalyze small-molecule reactions has driven their widespread application in organic chemistry. Here, we employ automated fast-flow solid-phase synthesis to access catalytically active full-length enzymes...
4.
Callahan A, Rondon A, Reja R, Salazar L, Gandhesiri S, Rodriguez J, et al.
J Am Chem Soc
. 2024 Oct;
146(42):28696-28706.
PMID: 39393021
Understanding protein function is a cornerstone of modern biology. Research centers worldwide dedicate significant efforts to prepare individual proteins for study, the isolation and purification of which can take days...
5.
Takeuchi H, Shimshoni E, Gandhesiri S, Loas A, Pentelute B
Bioconjug Chem
. 2024 Oct;
PMID: 39360857
Biocompatible cross-coupling reactions enable the efficient covalent attachment of large biomolecules at near-stoichiometric ratios, ensuring the stability and integrity of the resulting products. We present an affinity-based peptide platform utilizing...
6.
Yesilcimen A, Callahan A, Travaline T, Gandhesiri S, Tokareva O, Loas A, et al.
J Org Chem
. 2024 Sep;
89(18):12886-12893.
PMID: 39255342
Tumor necrosis factor-α (TNF-α) plays a central role in immune response regulation. Because elevated TNF-α production is correlated with a range of diseases, inhibiting the interaction of this protein with...
7.
Kitahara K, Rondon A, Miller E, Mak H, Loas A, Pentelute B
bioRxiv
. 2024 Sep;
PMID: 39229199
Peptide-based therapeutics are currently in great demand but often suffer from rapid clearance and accumulation in off-target tissues which continue to present barriers in their clinical translation. Here, we developed...
8.
Gu X, Zhang Y, Zhang S, Wang L, Ye X, Occhialini G, et al.
Nature
. 2024 Aug;
634(8033):352-358.
PMID: 39208846
Amino acids are essential building blocks in biology and chemistry. Whereas nature relies on a small number of amino acid structures, chemists desire access to a vast range of structurally...
9.
Wang K, Singh J, Albin J, Pentelute B, Nolan E
ACS Chem Biol
. 2024 Aug;
19(9):1953-1962.
PMID: 39172990
Dysbiosis of the human gut microbiota is linked to numerous diseases. Understanding the molecular mechanisms by which microbes interact and compete with one another is required for developing successful strategies...
10.
Tao J, Dhanjee H, Gribble Jr M, Kottisch V, Rodriguez J, Brown J, et al.
J Am Chem Soc
. 2024 Jul;
146(29):20080-20085.
PMID: 39001844
The utility of antibody therapeutics is hampered by potential cross-reactivity with healthy tissue. Over the past decade, significant advances have been made in the design of activatable antibodies, which increase,...