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Bradley L Nilsson

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Articles 66
Citations 1059
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Recent Articles
1.
Jiang C, Miao T, Xing X, Schilling K, Lenhard N, Wang L, et al.
Adv Healthc Mater . 2025 Jan; :e2404975. PMID: 39840608
The Masquelet technique that combines a foreign body reaction (FBR)-induced vascularized tissue membrane with staged bone grafting for reconstruction of segmental bone defect has gained wide attention in Orthopedic surgery....
2.
Rangubpit W, Sungted S, Wong-Ekkabut J, Distaffen H, Nilsson B, Dias C
ACS Chem Neurosci . 2024 Aug; 15(18):3354-3362. PMID: 39172951
One of the mechanisms accounting for the toxicity of amyloid peptides in diseases like Alzheimer's and Parkinson's is the formation of pores on the plasma membrane of neurons. Here, we...
3.
Chiang W, Urban J, Yanchik-Slade F, Stout A, Hammond J, Nilsson B, et al.
ACS Chem Neurosci . 2024 Aug; 15(17):3124-3135. PMID: 39146244
Various oligomeric species of amyloid-beta have been proposed to play different immunogenic roles in the cellular pathology of Alzheimer's Disease. The dynamic interconversion between various amyloid oligomers and fibrillar assemblies...
4.
Nilsson B, Celebi Torabfam G, Dias C
J Phys Chem B . 2024 Mar; 128(14):3320-3328. PMID: 38447080
Protein self-assembly plays an important role in biological systems, accounting for the formation of mesoscopic structures that can be highly symmetric as in the capsid of viruses or disordered as...
5.
Jagrosse M, Baliga U, Jones C, Russell J, Garcia C, Najar R, et al.
Mol Pharm . 2023 Nov; 20(12):6090-6103. PMID: 37963105
Short-interfering RNA (siRNA) oligonucleotide therapeutics that modify gene expression by accessing RNA-interference (RNAi) pathways have great promise for the treatment of a range of disorders; however, their application in clinical...
6.
Chiang W, Urban J, Yanchik-Slade F, Stout A, Nilsson B, Gelbard H, et al.
bioRxiv . 2023 Sep; PMID: 37693630
Various oligomeric species of amyloid-beta have been proposed to play different immunogenic roles in the cellular pathology of Alzheimer's Disease. However, investigating the role of a homogenous single oligomeric species...
7.
Chiang W, Stout A, Yanchik-Slade F, Li H, Terrando N, Nilsson B, et al.
ACS Appl Nano Mater . 2023 Aug; 6(16):15094-15107. PMID: 37649833
Despite limited evidence for infection of SARS-CoV-2 in the central nervous system, cognitive impairment is a common complication reported in "recovered" COVID-19 patients. Identification of the origins of these neurological...
8.
Jagrosse M, Agredo P, Abraham B, Toriki E, Nilsson B
ACS Biomater Sci Eng . 2023 Jan; 9(2):784-796. PMID: 36693219
Protein-based therapeutics have emerged as next-generation pharmaceutical agents for oncology, bone regeneration, autoimmune disorders, viral infections, and other diseases. The clinical application of protein therapeutics has been impeded by pharmacokinetic...
9.
Abraham B, Agredo P, Mensah S, Nilsson B
Langmuir . 2022 Dec; 38(50):15494-15505. PMID: 36473193
Supramolecular hydrogels have emerged as a class of promising biomaterials for applications such as drug delivery and tissue engineering. Self-assembling peptides have been well studied for such applications, but low...
10.
Yang Y, Distaffen H, Jalali S, Nieuwkoop A, Nilsson B, Dias C
ACS Chem Neurosci . 2022 Sep; 13(18):2766-2777. PMID: 36095304
Amphipathic peptides can cause biological membranes to leak either by dissolving their lipid content via a detergent-like mechanism or by forming pores on the membrane surface. These modes of membrane...