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Bradley A Schulte

Explore the profile of Bradley A Schulte including associated specialties, affiliations and a list of published articles. Areas
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Articles 47
Citations 1313
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Recent Articles
11.
Zhong G, Qin S, Townsend D, Schulte B, Tew K, Wang G
Biochem Biophys Res Commun . 2019 May; 514(4):1204-1209. PMID: 31109646
Cancer stem cells (CSCs) have been shown to be resistant to current anticancer therapies and the induction of oxidative stress is an important mechanism of action for many anticancer agents....
12.
Qin S, Schulte B, Wang G
World J Clin Oncol . 2019 Jan; 9(8):180-187. PMID: 30622926
Cellular senescence is a form of permanent cell cycle arrest that can be triggered by a variety of cell-intrinsic and extrinsic stimuli, including telomere shortening, DNA damage, oxidative stress, and...
13.
Lewis M, Nolan L, Cadge B, Matthews L, Schulte B, Dubno J, et al.
BMC Med Genomics . 2018 Sep; 11(1):77. PMID: 30180840
Background: Deafness is a highly heterogenous disorder with over 100 genes known to underlie human non-syndromic hearing impairment. However, many more remain undiscovered, particularly those involved in the most common...
14.
Klauber-DeMore N, Schulte B, Wang G
Oncoscience . 2018 Jul; 5(5-6):120-121. PMID: 30035158
No abstract available.
15.
Panganiban C, Barth J, Darbelli L, Xing Y, Zhang J, Li H, et al.
J Neurosci . 2018 Feb; 38(10):2551-2568. PMID: 29437856
Noise exposure causes auditory nerve (AN) degeneration and hearing deficiency, though the proximal biological consequences are not entirely understood. Most AN fibers and spiral ganglion neurons are ensheathed by myelinating...
16.
He X, Yang A, McDonald D, Riemer E, Vanek K, Schulte B, et al.
Oncotarget . 2017 Oct; 8(41):69797-69807. PMID: 29050242
MicroRNAs (miRNAs) are a new class of gene expression regulators that have been implicated in tumorigenesis and modulation of the responses to cancer treatment including that of human non-small cell...
17.
Yang A, Qin S, Schulte B, Ethier S, Tew K, Wang G
Cancer Res . 2017 Sep; 77(23):6641-6650. PMID: 28951456
There is mounting evidence that cancer stem-like cells (CSC) are selectively enriched in residual tumors after anticancer therapies, which may account for tumor recurrence and metastasis by regenerating new tumors....
18.
Lang H, Nishimoto E, Xing Y, Brown L, Noble K, Barth J, et al.
Mol Ther . 2016 Sep; 24(11):2000-2011. PMID: 27600399
The peripheral auditory nerve (AN) carries sound information from sensory hair cells to the brain. The present study investigated the contribution of mouse and human hematopoietic stem cells (HSCs) to...
19.
Yang A, Xiao X, Zhao M, LaRue A, Schulte B, Wang G
Stem Cells Int . 2015 Jul; 2015:561404. PMID: 26221145
Abnormal activation of the mammalian target of rapamycin (mTOR) signaling pathway has been observed in a variety of human cancers. Therefore, targeting of the mTOR pathway is an attractive strategy...
20.
Xiao X, Luo H, Vanek K, LaRue A, Schulte B, Wang G
Stem Cells Dev . 2015 Jan; 24(11):1342-51. PMID: 25603016
Hematologic toxicity is a major cause of mortality in radiation emergency scenarios and a primary side effect concern in patients undergoing chemo-radiotherapy. Therefore, there is a critical need for the...