Gavin Y Wang
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Explore the profile of Gavin Y Wang including associated specialties, affiliations and a list of published articles.
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19
Citations
491
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Recent Articles
1.
Wang Y, Zhou X, Lei Y, Chu Y, Yu X, Tong Q, et al.
Cancer Lett
. 2025 Jan;
:217424.
PMID: 39755471
No abstract available.
2.
Wang Y, Zhou X, Lei Y, Chu Y, Yu X, Tong Q, et al.
Cancer Lett
. 2022 Aug;
547:215884.
PMID: 35988817
Elucidating the mechanism for high metastasis capacity of triple negative breast cancers (TNBC) is crucial to improve treatment outcomes of TNBC. We have recently reported that nicotinamide N-methyltransferase (NNMT) is...
3.
Lin H, Dixon S, Hu W, Hamlett E, Jin J, Ergul A, et al.
Mol Neurobiol
. 2022 Jun;
59(9):5284-5298.
PMID: 35697992
The accumulation of amyloid beta (Aβ) plaques in the brain is a hallmark of Alzheimer's disease (AD) pathology. Microglial activation-mediated neuroinflammation has been implicated in the pathogenesis of AD and...
4.
Cook M, Lin H, Mishra S, Wang G
Biochem Biophys Res Commun
. 2022 Jun;
617(Pt 1):30-35.
PMID: 35671608
The accumulation of senescent cells in aged tissues has been implicated in a variety of age-related diseases, including cancer and neurodegenerative disorders. Recent studies have demonstrated a link between age-associated...
5.
Nrf2 inhibition sensitizes breast cancer stem cells to ionizing radiation via suppressing DNA repair
Qin S, He X, Lin H, Schulte B, Zhao M, Tew K, et al.
Free Radic Biol Med
. 2021 Apr;
169:238-247.
PMID: 33892113
Radiation is widely used for cancer treatment but the radioresistance properties of cancer stem cells (CSCs) pose a significant challenge to the success of cancer therapy. Nuclear factor erythroid-2-related factor...
6.
Bartolini D, Tew K, Marinelli R, Galli F, Wang G
Biofactors
. 2019 Oct;
46(2):239-245.
PMID: 31617634
The trace element selenium (Se) is an essential component of selenoproteins and plays a critical role in redox signaling via regulating the activity of selenoenzymes such as thioredoxin reductase-1 and...
7.
Zhang L, Zhang J, Ye Z, Manevich Y, Ball L, Bethard J, et al.
Cancer Res
. 2019 Jun;
79(16):4072-4085.
PMID: 31227482
ME-344 is a second-generation isoflavone with unusual cytotoxic properties that is in clinical testing in cancer. To identify targets that contribute to its anticancer activity and therapeutic index, we used...
8.
Zhong G, Qin S, Townsend D, Schulte B, Tew K, Wang G
Biochem Biophys Res Commun
. 2019 May;
514(4):1204-1209.
PMID: 31109646
Cancer stem cells (CSCs) have been shown to be resistant to current anticancer therapies and the induction of oxidative stress is an important mechanism of action for many anticancer agents....
9.
Wang Y, Zeng J, Wu W, Xie S, Yu H, Li G, et al.
Breast Cancer Res
. 2019 May;
21(1):64.
PMID: 31101119
Background: Nicotinamide N-methyltransferase (NNMT) is overexpressed in various human tumors and involved in the development and progression of several carcinomas. In breast cancer, NNMT was found to be overexpressed in...
10.
Bartolini D, Wang Y, Zhang J, Giustarini D, Rossi R, Wang G, et al.
PLoS One
. 2019 Apr;
14(4):e0205626.
PMID: 31034521
2,2'-diselenyldibenzoic acid (DSBA) is a chemical probe produced to explore the pharmacological properties of diphenyldiselenide-derived agents with seleno-hormetic activity undergoing preclinical development. The present study was designed to verify in...