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Amanda C LaRue

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Articles 63
Citations 1220
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Recent Articles
1.
Corker A, Troncoso M, Learmonth M, Broughton P, Sidles S, Kelly R, et al.
J Mol Cell Cardiol . 2025 Feb; 201:32-43. PMID: 39970739
Post-traumatic stress disorder (PTSD) is a disabling psychological disorder characterized by chronic symptoms of intrusiveness, avoidance, and hyperarousal after a traumatic event. Retrospective studies have indicated PTSD increases the risk...
2.
Li P, Liu L, Liu S, Lu Z, Halushka P, Sidles S, et al.
Front Psychiatry . 2024 Aug; 15:1436690. PMID: 39140108
Post-traumatic stress disorder (PTSD) is a debilitating psychiatric condition with significant public health implications that arise following exposure to traumatic events. Recent studies highlight the involvement of immune dysregulation in...
3.
Sidles S, Kelly R, Kelly K, Hathaway-Schrader J, Khoo S, Jones J, et al.
Dis Model Mech . 2023 Dec; 17(1). PMID: 38131122
Post-traumatic stress disorder (PTSD) is associated with osteopenia, osteoporosis and increased fracture risk in the clinical population. Yet, the development of preclinical models to study PTSD-induced bone loss remains limited....
4.
Kuhn M, VandenBerg H, Reynolds A, Carson M, Warner A, LaRue A, et al.
Bone Rep . 2023 Mar; 18:101662. PMID: 36860797
Osteoimmune studies have identified complement signaling as an important regulator of the skeleton. Specifically, complement anaphylatoxin receptors (i.e., C3aR, C5aR) are expressed on osteoblasts and osteoclasts, implying that C3a and/or...
5.
Boyce M, Durham E, Kuo S, Taylor J, Kishinchand R, LaRue A, et al.
Orthod Craniofac Res . 2022 Dec; 26(3):415-424. PMID: 36458927
Objectives: Antidepressants, specifically Selective Serotonin Re-uptake Inhibitors (SSRIs), that alter serotonin metabolism are currently the most commonly prescribed drugs for the treatment of depression. There is some evidence to suggest...
6.
Jensen N, Kelly R, Kelly K, Khoo S, Sidles S, LaRue A
Calcif Tissue Int . 2022 Nov; 112(4):403-421. PMID: 36422682
Src homology-2 domain-containing phosphatase 2 (SHP2) is a ubiquitously expressed phosphatase that is vital for skeletal development and maintenance of chondrocytes, osteoblasts, and osteoclasts. Study of SHP2 function in small...
7.
Dhupar R, Jones K, Powers A, Eisenberg S, Ding K, Chen F, et al.
Front Immunol . 2022 Jun; 13:830169. PMID: 35651620
Tumor-associated macrophages (TAMs) exert profound influence over breast cancer progression, promoting immunosuppression, angiogenesis, and metastasis. Neuropilin-2 (NRP2), consisting of the NRP2a and NRP2b isoforms, is a co-receptor for heparin-binding growth...
8.
Powers A, Jones K, Eisenberg S, Rigatti L, Ryan J, Luketich J, et al.
Life Sci . 2021 Jul; 282:119839. PMID: 34293400
Aims: Respiratory disorders are a prominent component of Gulf War Illness. Although much of the underlying mechanisms of Gulf War Illness remain undefined, chronic immune dysfunction is a consistent feature...
9.
Kang I, Baliga U, Wu Y, Mehrotra S, Yao H, LaRue A, et al.
Stem Cells . 2021 Jul; 39(11):1457-1477. PMID: 34224636
Currently, there is no cure for osteogenesis imperfecta (OI)-a debilitating pediatric skeletal dysplasia. Herein we show that hematopoietic stem cell (HSC) therapy holds promise in treating OI. Using single-cell HSC...
10.
Kelly R, Sidles S, LaRue A
Front Psychol . 2021 Jan; 11:612366. PMID: 33424724
Neurological diseases, particularly in the context of aging, have serious impacts on quality of life and can negatively affect bone health. The brain-bone axis is critically important for skeletal metabolism,...