Bostjan Markelc
Overview
Explore the profile of Bostjan Markelc including associated specialties, affiliations and a list of published articles.
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61
Citations
886
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Recent Articles
1.
De Robertis M, Bozic T, Santek I, Marzano F, Markelc B, Silvestris D, et al.
Mol Ther Nucleic Acids
. 2025 Feb;
36(1):102448.
PMID: 39967849
Gene electrotransfer (GET) has recently emerged as an effective nonviral approach for plasmid DNA (pDNA) delivery in gene therapy for several pathologies, including cancer. Multiple mechanisms have been identified that...
2.
Strojan P, Jesenko T, Omerzel M, Jamsek C, Groselj A, Tratar U, et al.
Eur J Surg Oncol
. 2025 Jan;
51(5):109574.
PMID: 39799833
Introduction: In the treatment of cancer, immunomodulatory approaches are developed to support the organism in fighting cancer or to enhance the immunomodulatory effects of local ablative techniques. To this end,...
3.
Tomanic T, Stergar J, Bozic T, Markelc B, Brezar S, Sersa G, et al.
Heliyon
. 2024 Nov;
10(21):e39816.
PMID: 39553684
The non-invasive monitoring of tumor growth can offer invaluable diagnostic insights and enhance our understanding of tumors and their microenvironment. Integrating hyperspectral imaging (HSI) with three-dimensional optical profilometry (3D OP)...
4.
Markelc B, Jesenko T, Brezar S, Omerzel M, Tratar U, Rencelj A, et al.
Sci Rep
. 2024 Sep;
14(1):22288.
PMID: 39333733
Immunotherapeutic drugs are promising medicines for cancer treatment. A potential candidate for immunotherapy is interleukin-12 (IL-12), a cytokine well known for its ability to mediate antitumor activity. We developed a...
5.
Della Pelle G, Bozic T, Vukomanovic M, Sersa G, Markelc B, Kostevsek N
Nanoscale Adv
. 2024 Sep;
6(18):4704-4723.
PMID: 39263399
Small-interfering RNAs (siRNAs) are therapeutic nucleic acids, often delivered cationic polymers, liposomes, or extracellular vesicles, each method with its limitations. Genipin, a natural crosslinker for primary amines, was explored for...
6.
Tomanic T, Bozic T, Markelc B, Stergar J, Sersa G, Milanic M
J Biomed Opt
. 2024 Jul;
29(9):093504.
PMID: 39040986
Significance: Hyperspectral imaging (HSI) of murine tumor models grown in dorsal skinfold window chambers (DSWCs) offers invaluable insight into the tumor microenvironment. However, light loss in a glass coverslip is...
7.
Prelog T, Bucek S, Brozic A, Peterlin J, Kavcic M, Omerzel M, et al.
Radiol Oncol
. 2024 Feb;
58(1):133-144.
PMID: 38378030
Background: Flow cytometry plays is important in the diagnosis of acute lymphoblastic leukaemia (ALL) and when antigen-specific immunotherapy is indicated. We have investigated the effects of prednisolone, vincristine, daunorubicin, asparaginase...
8.
Kory J, Narain V, Stolz B, Kaeppler J, Markelc B, Muschel R, et al.
PLoS Comput Biol
. 2024 Feb;
20(2):e1011252.
PMID: 38363799
Tumour angiogenesis leads to the formation of blood vessels that are structurally and spatially heterogeneous. Poor blood perfusion, in conjunction with increased hypoxia and oxygen heterogeneity, impairs a tumour's response...
9.
Lisec B, Bozic T, Santek I, Markelc B, Vrecl M, Frangez R, et al.
Cell Commun Signal
. 2024 Feb;
22(1):118.
PMID: 38347539
Background: Disruption of Ca homeostasis after calcium electroporation (CaEP) in tumors has been shown to elicit an enhanced antitumor effect with varying impacts on healthy tissue, such as endothelium. Therefore,...
10.
Bozic T, Markelc B
Methods Mol Biol
. 2024 Jan;
2773:137-155.
PMID: 38236543
Infiltration of immune cells into the tumor is one of the major drivers of antitumor immune response, which can direct the outcome of anticancer therapies. In mice, implantation of dorsal...