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Simona Kranjc Brezar

Explore the profile of Simona Kranjc Brezar including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 60
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Recent Articles
1.
Ursic Valentinuzzi K, Kamensek U, Brezar S, Heranney C, Komel T, Bucek S, et al.
Front Immunol . 2025 Feb; 16:1470432. PMID: 40007542
Introduction: In addition to its direct cytotoxic effects, ablative therapies as electrochemotherapy (ECT) can elicit indirect antitumor effects by triggering immune system responses. Here, we comprehensively analyzed this dual effectiveness...
2.
Scattolin T, Cavarzerani E, Alessi D, Mauceri M, Botter E, Tonon G, et al.
Dalton Trans . 2025 Feb; 54(11):4685-4696. PMID: 39967474
High-Grade Serous Ovarian Cancer (HGSOC) is the most common and lethal subtype of ovarian cancer, known for its high aggressiveness and extensive genomic alterations. Typically diagnosed at an advanced stage,...
3.
Tomanic T, Stergar J, Bozic T, Markelc B, Brezar S, Sersa G, et al.
Heliyon . 2024 Nov; 10(21):e39816. PMID: 39553684
The non-invasive monitoring of tumor growth can offer invaluable diagnostic insights and enhance our understanding of tumors and their microenvironment. Integrating hyperspectral imaging (HSI) with three-dimensional optical profilometry (3D OP)...
4.
Markelc B, Jesenko T, Brezar S, Omerzel M, Tratar U, Rencelj A, et al.
Sci Rep . 2024 Sep; 14(1):22288. PMID: 39333733
Immunotherapeutic drugs are promising medicines for cancer treatment. A potential candidate for immunotherapy is interleukin-12 (IL-12), a cytokine well known for its ability to mediate antitumor activity. We developed a...
5.
Hren R, Brezar S, Marhl U, Sersa G
Radiol Oncol . 2024 Sep; 58(3):326-334. PMID: 39287164
Background: Laser speckle coherence imaging (LSCI) is an emerging imaging modality that enables noninvasive visualization and assessment of tissue perfusion and microcirculation. In this article, we evaluated LSCI in imaging...
6.
Dobaja Borak M, Leonardi A, Pozek K, Rebersek K, Podgornik H, Pirnat A, et al.
Thromb Haemost . 2024 Sep; PMID: 39227033
Profound and transient thrombocytopenia of functional platelets without bleeding was observed in patients envenomed by (). This condition was rapidly reversed by administration of F(ab) fragments of immunoglobulin G targeting...
7.
Dobovisek L, Borstnar S, Debeljak N, Brezar S
Front Immunol . 2024 Aug; 15:1386548. PMID: 39176080
Triple-negative breast cancer (TNBC) accounts for about 10-20% of all breast cancer cases and is associated with an unfavorable prognosis. Until recently, treatment options for TNBC were limited to chemotherapy....
8.
Bortolamiol E, Mauceri M, Piccolo R, Cavarzerani E, Demitri N, Donati C, et al.
J Med Chem . 2024 Aug; 67(16):14414-14431. PMID: 39119630
In this study, we synthesized novel Pd(II)-indenyl complexes using various -heterocyclic carbene (NHC) ligands, including chelating NHC-picolyl, NHC-thioether, and diNHC ligands, and two monodentate NHCs. Transmetalation reactions between a Pd(II)-indenyl...
9.
Palazzolo S, Saorin G, Corona G, Granchi C, Tuccinardi T, Kamensek U, et al.
Eur J Pharm Biopharm . 2024 Jul; 203:114397. PMID: 38972466
Monoacylglycerol lipase (MAGL) is a promising target for cancer therapy due to its involvement in lipid metabolism and its impact on cancer hallmarks like cell proliferation, migration, and tumor progression....
10.
Brisar N, Suster K, Brezar S, Vidmar R, Fonovic M, Cor A
Viruses . 2024 Feb; 16(2). PMID: 38400008
Bacteriophages, prokaryotic viruses, hold great potential in genetic engineering to open up new avenues for vaccine development. Our study aimed to establish engineered M13 bacteriophages expressing MAGE-A1 tumor peptides as...