Boris L Vaisman
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Explore the profile of Boris L Vaisman including associated specialties, affiliations and a list of published articles.
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20
Citations
402
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Recent Articles
1.
Amar M, Freeman L, Nishida T, Sampson M, Pryor M, Vaisman B, et al.
Pharmacol Res Perspect
. 2020 Jan;
8(1):e00554.
PMID: 31893124
Familial lecithin:cholesterol acyltransferase (LCAT) deficiency (FLD) is a rare genetic disease characterized by low HDL-C levels, low plasma cholesterol esterification, and the formation of Lipoprotein-X (Lp-X), an abnormal cholesterol-rich lipoprotein...
2.
Komatsu T, Sakurai T, Wolska A, Amar M, Sakurai A, Vaisman B, et al.
J Nutr Metab
. 2019 Mar;
2019:7078241.
PMID: 30863636
Aim: Plasma apolipoprotein C-II (apoC-II) activates lipoprotein lipase (LPL) and thus lowers plasma triglycerides (TG). We previously reported that a human apoC-II mimetic peptide (C-II-a) decreased plasma TG in apoC-II...
3.
Vaisman B, Neufeld E, Freeman L, Gordon S, Sampson M, Pryor M, et al.
J Pharmacol Exp Ther
. 2018 Dec;
368(3):423-434.
PMID: 30563940
Familial LCAT deficiency (FLD) is due to mutations in lecithin:cholesterol acyltransferase (LCAT), a plasma enzyme that esterifies cholesterol on lipoproteins. FLD is associated with markedly reduced levels of plasma high-density...
4.
Liu C, Han T, Stachura D, Wang H, Vaisman B, Kim J, et al.
Nat Commun
. 2018 Apr;
9(1):1310.
PMID: 29615667
Lipoprotein lipase (LPL) mediates hydrolysis of triglycerides (TGs) to supply free fatty acids (FFAs) to tissues. Here, we show that LPL activity is also required for hematopoietic stem progenitor cell...
5.
Sakurai T, Sakurai A, Vaisman B, Nishida T, Neufeld E, Demosky Jr S, et al.
Ann Clin Biochem
. 2017 Sep;
55(4):414-421.
PMID: 28882064
Background Lecithin:cholesterol acyltransferase (LCAT) is a plasma enzyme that esterifies cholesterol. Recombinant human LCAT (rhLCAT) is now being developed as an enzyme replacement therapy for familial LCAT deficiency and as...
6.
Freeman L, Demosky Jr S, Konaklieva M, Kuskovsky R, Aponte A, Ossoli A, et al.
J Pharmacol Exp Ther
. 2017 Jun;
362(2):306-318.
PMID: 28576974
Lecithin:cholesterol acyltransferase (LCAT) catalyzes plasma cholesteryl ester formation and is defective in familial lecithin:cholesterol acyltransferase deficiency (FLD), an autosomal recessive disorder characterized by low high-density lipoprotein, anemia, and renal disease....
7.
Baranova I, Souza A, Bocharov A, Vishnyakova T, Hu X, Vaisman B, et al.
PLoS One
. 2017 Apr;
12(4):e0175824.
PMID: 28423002
Serum amyloid A (SAA) is an acute phase protein with cytokine-like and chemotactic properties, that is markedly up-regulated during various inflammatory conditions. Several receptors, including FPRL-1, TLR2, TLR4, RAGE, class...
8.
Sakurai T, Sakurai A, Chen Y, Vaisman B, Amar M, Pryor M, et al.
Mol Nutr Food Res
. 2017 Jan;
61(8).
PMID: 28102587
Scope: α-Cyclodextrin (α-CD), a cyclic polymer of glucose, has been shown to lower plasma cholesterol in animals and humans; however, its effect on atherosclerosis has not been previously described. Methods...
9.
Sorokin A, Yang Z, Vaisman B, Thacker S, Yu Z, Sampson M, et al.
J Nutr Biochem
. 2016 Jul;
35:58-65.
PMID: 27394692
Aspirin (ASA) is known to alter the production of potent inflammatory lipid mediators, but whether it interacts with omega-3 fatty acids (FAs) from fish oil to affect atherosclerosis has not...
10.
Baranova I, Souza A, Bocharov A, Vishnyakova T, Hu X, Vaisman B, et al.
J Immunol
. 2016 Mar;
196(7):3135-47.
PMID: 26936883
The class B scavenger receptors BI (SR-BI) and BII (SR-BII) are high-density lipoprotein receptors that recognize various pathogens, including bacteria and their products. It has been reported that SR-BI/II null...