Boris Ferger
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Explore the profile of Boris Ferger including associated specialties, affiliations and a list of published articles.
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62
Citations
1069
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Recent Articles
1.
Wang X, Wu X, Wu H, Xiao H, Hao S, Wang B, et al.
Sci Adv
. 2023 Nov;
9(44):eadh2884.
PMID: 37910621
Overeating disorders largely contribute to worldwide incidences of obesity. Available treatments are limited. Here, we discovered that long-term chemogenetic activation of ventrolateral periaqueductal gray (vlPAG) GABAergic cells rescue obesity of...
2.
Deiana S, Hauber W, Munster A, Sommer S, Ferger B, Marti A, et al.
Eur J Pharmacol
. 2022 Oct;
935:175306.
PMID: 36183855
N-methyl-D-aspartate-receptor (NMDAR) hypofunction contributes to cognitive impairments in neuropsychiatric disorders such as schizophrenia. Reduced NMDAR signalling can be enhanced by increasing extracellular levels of the NMDAR co-agonist glycine through inhibition...
3.
Munster A, Sommer S, Kukelova D, Sigrist H, Koros E, Deiana S, et al.
Neuropharmacology
. 2022 May;
213:109078.
PMID: 35561791
Apathy, deficiency of motivation including willingness to exert effort for reward, is a common symptom in many psychiatric and neurological disorders, including depression and schizophrenia. Despite improved understanding of the...
4.
Cruces-Solis H, Nissen W, Ferger B, Arban R
Neuropharmacology
. 2020 Aug;
178:108246.
PMID: 32771528
While neuropsychiatric drugs influence neural activity across multiple brain regions, the current understanding of their mechanism of action derives from studies that investigate an influence of a given drug onto...
5.
Raith H, Schuelert N, Duveau V, Roucard C, Plano A, Dorner-Ciossek C, et al.
Neuropharmacology
. 2020 Apr;
171:108072.
PMID: 32243874
Quantitative Electroencephalography (qEEG) and event-related potential (ERP) assessment have emerged as powerful tools to unravel translational biomarkers in preclinical and clinical psychiatric drug discovery trials. The aim of the present...
6.
Kiechle M, von Einem B, Hofs L, Voehringer P, Grozdanov V, Markx D, et al.
Cell Rep
. 2019 Nov;
29(9):2862-2874.e9.
PMID: 31775051
Intracellular accumulation of α-synuclein (α-syn) and formation of Lewy bodies are neuropathological characteristics of Parkinson's disease (PD) and related α-synucleinopathies. Oligomerization and spreading of α-syn from neuron to neuron have...
7.
Kofler M, Schiefecker A, Gaasch M, Sperner-Unterweger B, Fuchs D, Beer R, et al.
Sci Rep
. 2019 Feb;
9(1):2811.
PMID: 30808966
The amino-acids tryptophan, phenylalanine and tyrosine seem to play an important role in the pathophysiology of depressive disorders. We measured daily brain extracellular levels of these amino-acids using cerebral microdialysis...
8.
Soyal S, Zara G, Ferger B, Felder T, Kwik M, Nofziger C, et al.
Neurobiol Dis
. 2018 Sep;
121:34-46.
PMID: 30236862
Parkinson's disease (PD) is the second most common neurodegenerative disease worldwide. PGC-1α, encoded by PPARGC1A, is a transcriptional co-activator that has been implicated in the pathogenesis of neurodegenerative disorders. We...
9.
Bergamini G, Mechtersheimer J, Azzinnari D, Sigrist H, Buerge M, Dallmann R, et al.
Neurobiol Stress
. 2018 Jun;
8:42-56.
PMID: 29888303
Psychosocial stress is a major risk factor for depression, stress leads to peripheral and central immune activation, immune activation is associated with blunted dopamine (DA) neural function, DA function underlies...
10.
Kritzinger A, Ferger B, Gillardon F, Stierstorfer B, Birk G, Kochanek S, et al.
Neurobiol Aging
. 2018 Mar;
66:97-111.
PMID: 29550548
Mutations in leucine-rich repeat kinase 2 (LRRK2) age-dependently cause Parkinson's disease and are associated with several inflammatory diseases. So far, the potential role of LRRK2 expression in glial cells as...