Patrizia Voehringer
Overview
Explore the profile of Patrizia Voehringer including associated specialties, affiliations and a list of published articles.
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9
Citations
91
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Recent Articles
1.
Reed C, Kalbfleisch J, Turkett J, Trombley T, Nastase A, Spearing P, et al.
J Med Chem
. 2024 Dec;
67(24):22291-22312.
PMID: 39665415
Herein, we report progress toward a metabotropic glutamate receptor subtype 1 (mGlu) positive allosteric modulator (PAM) clinical candidate and the discovery of VU6024578/BI02982816. From a weak high-throughput screening hit (VU0538160,...
2.
Ahuis T, Smyk M, Laloux C, Aulehner K, Bray J, Waldron A, et al.
PLoS One
. 2024 Oct;
19(10):e0309521.
PMID: 39471212
The European Quality In Preclinical Data (EQIPD) consortium was born from the fact that publications report challenges with the robustness, rigor, and/or validity of research data, which may impact decisions...
3.
Kiechle M, von Einem B, Hofs L, Voehringer P, Grozdanov V, Markx D, et al.
Cell Rep
. 2019 Nov;
29(9):2862-2874.e9.
PMID: 31775051
Intracellular accumulation of α-synuclein (α-syn) and formation of Lewy bodies are neuropathological characteristics of Parkinson's disease (PD) and related α-synucleinopathies. Oligomerization and spreading of α-syn from neuron to neuron have...
4.
Voehringer P, Nicholson J
Handb Exp Pharmacol
. 2019 Sep;
257:197-222.
PMID: 31541320
Data quality, reproducibility and reliability are a matter of concern in many scientific fields including biomedical research. Robust, reproducible data and scientific rigour form the foundation on which future studies...
5.
Pasquarelli N, Voehringer P, Henke J, Ferger B
Behav Brain Res
. 2017 Jun;
333:35-42.
PMID: 28625548
The development of modern housing regimes such as individually ventilated cage (IVC) systems has become very popular and attractive in order to reduce spreading of pathogenic organisms and to lower...
6.
Voehringer P, Fuertig R, Ferger B
J Chromatogr B Analyt Technol Biomed Life Sci
. 2013 Oct;
939:92-7.
PMID: 24121745
Glycine is an important amino acid neurotransmitter in the central nervous system (CNS) and a useful biomarker to indicate biological activity of drugs such as glycine reuptake inhibitors (GRI) in...
7.
Ferger B, Buck K, Shimasaki M, Koros E, Voehringer P, Buerger E
Synapse
. 2010 Mar;
64(7):533-41.
PMID: 20196139
Short-acting dopamine (DA) agonists are usually administered several times a day resulting in fluctuating plasma and brain levels. DA agonists providing continuous dopaminergic stimulation may achieve higher therapeutic benefit for...
8.
Buck K, Voehringer P, Ferger B
J Neurochem
. 2009 Nov;
112(2):444-52.
PMID: 19895663
L-DOPA-induced dyskinesia is characterised by debilitating involuntary movement, which limits quality of life in patients suffering from Parkinson's disease. Here, we investigate effects of the a2 adrenoceptor antagonist idazoxan on...
9.
Buck K, Voehringer P, Ferger B
J Neurosci Methods
. 2009 Jun;
182(1):78-84.
PMID: 19505500
A liquid chromatography/tandem mass spectrometry (LC-MS/MS) method has been established for the rapid and reliable determination of gamma-aminobutyric acid (GABA) and glutamate in brain microdialysates. The microdialysis samples were analysed...