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Bastian Hengerer

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Articles 84
Citations 2313
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Recent Articles
1.
Mantas I, Flais I, Branzell N, Ionescu T, Kim E, Zhang X, et al.
Neuropsychopharmacology . 2025 Feb; PMID: 39934408
The atypical antipsychotic clozapine targets multiple receptor systems beyond the dopaminergic pathway and influences prepulse inhibition (PPI), a critical translational measure of sensorimotor gating. Since PPI is modulated by atypical...
2.
Stoller F, Hinds E, Ionescu T, Khatamsaz E, Marston H, Hengerer B
Sci Rep . 2024 Dec; 14(1):30492. PMID: 39681620
The PRISM project, funded by the EU's Innovative Medicines Initiative, has identified a transdiagnostic, pathophysiological relationship between the integrity of the default mode network (DMN) and social dysfunction. To explore...
3.
Mould A, Wright D, Bornemann K, Hengerer B, Pinnock R, Drydale E, et al.
Cereb Cortex . 2024 Dec; 34(12). PMID: 39656879
Kalirin is a multidomain protein with important roles in neurite outgrowth, and synaptic spine formation and remodeling. Genetic and pathophysiological links with various neuropsychiatric disorders associated with synaptic dysfunction and...
4.
Santa C, Park S, Gejt A, Clark H, Hengerer B, Sergelen K
Analyst . 2024 Nov; 150(1):131-141. PMID: 39584594
Real-time monitoring of therapeutic drugs is crucial for treatment management and pharmacokinetic studies. We present the optimization and affinity tuning of split-aptamer sandwich assay for real-time monitoring of the narrow...
5.
Mantas I, Flais I, Masarapu Y, Ionescu T, Frapard S, Jung F, et al.
Nat Commun . 2024 Sep; 15(1):8176. PMID: 39289358
The Claustrum/dorsal endopiriform cortex complex (CLA) is an enigmatic brain region with extensive glutamatergic projections to multiple cortical areas. The transcription factor Nurr1 is highly expressed in the CLA, but...
6.
Zhang C, Kukelova D, Sigrist H, Hengerer B, Kratzer R, Mracek P, et al.
Transl Psychiatry . 2024 Sep; 14(1):363. PMID: 39242529
Reward processing dysfunctions e.g., anhedonia, apathy, are common in stress-related neuropsychiatric disorders including depression and schizophrenia, and there are currently no established therapies. One potential therapeutic approach is restoration of...
7.
Zhang C, Dulinskas R, Ineichen C, Greter A, Sigrist H, Li Y, et al.
Commun Biol . 2024 Aug; 7(1):966. PMID: 39123076
Whilst reward pathologies are major and common in stress-related neuropsychiatric disorders, their neurobiology and treatment are poorly understood. Imaging studies in human reward pathology indicate attenuated BOLD activity in nucleus...
8.
Kapanaiah S, Rosenbrock H, Hengerer B, Katzel D
Front Pharmacol . 2024 Jul; 15:1412725. PMID: 39045050
Background: Neuropsychopharmacological compounds may exert complex brain-wide effects due to an anatomically and genetically broad expression of their molecular targets and indirect effects interconnected brain circuits. Electrophysiological measurements in multiple...
9.
Poggi G, Bergamini G, Dulinskas R, Madur L, Greter A, Ineichen C, et al.
Eur J Neurosci . 2024 Feb; 59(5):996-1015. PMID: 38326849
Basal amygdala (BA) neurons projecting to nucleus accumbens (NAc) core/shell are primarily glutamatergic and are integral to the circuitry of emotional processing. Several recent mouse studies have addressed whether neurons...
10.
Hinchcliffe J, Stuart S, Wood C, Bartlett J, Kamenish K, Arban R, et al.
Sci Transl Med . 2024 Jan; 16(729):eadi2403. PMID: 38198569
How rapid-acting antidepressants (RAADs), such as ketamine, induce immediate and sustained improvements in mood in patients with major depressive disorder (MDD) is poorly understood. A core feature of MDD is...