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Bo Curry

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Articles 11
Citations 592
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Recent Articles
1.
Ryan D, Diamant-Levi T, Steinfeld I, Taussig D, Visal-Shah S, Thakker S, et al.
Biochemistry . 2022 Apr; 62(24):3512-3520. PMID: 35436085
CRISPR gene editing and control systems continue to emerge and inspire novel research and clinical applications. Advances in CRISPR performance such as optimizing the duration of activity in cells, tissues,...
2.
Cromer M, Vaidyanathan S, Ryan D, Curry B, Bergstrom Lucas A, Camarena J, et al.
Mol Ther . 2018 Jul; 26(10):2431-2442. PMID: 30005866
Genome-editing technologies are currently being translated to the clinic. However, cellular effects of the editing machinery have yet to be fully elucidated. Here, we performed global microarray-based gene expression measurements...
3.
Ryan D, Taussig D, Steinfeld I, Phadnis S, Lunstad B, Singh M, et al.
Nucleic Acids Res . 2017 Dec; 46(2):792-803. PMID: 29216382
CRISPR systems have emerged as transformative tools for altering genomes in living cells with unprecedented ease, inspiring keen interest in increasing their specificity for perfectly matched targets. We have developed...
4.
Hsiau T, Sukovich D, Elms P, Prince R, Strittmatter T, Ruan P, et al.
PLoS One . 2015 May; 10(5):e0126078. PMID: 25945930
No abstract available.
5.
Hsiau T, Sukovich D, Elms P, Prince R, Strittmatter T, Stritmatter T, et al.
PLoS One . 2015 Mar; 10(3):e0119927. PMID: 25790188
Our ability to engineer organisms with new biosynthetic pathways and genetic circuits is limited by the availability of protein characterization data and the cost of synthetic DNA. With new tools...
6.
Gresham D, Curry B, Ward A, Gordon D, Brizuela L, Kruglyak L, et al.
Proc Natl Acad Sci U S A . 2010 Jan; 107(4):1482-7. PMID: 20080586
The use of DNA microarrays to identify nucleotide variation is almost 20 years old. A variety of improvements in probe design and experimental conditions have brought this technology to the...
7.
Ach R, Wang H, Curry B
BMC Biotechnol . 2008 Sep; 8:69. PMID: 18783629
Background: Determining the expression levels of microRNAs (miRNAs) is of great interest to researchers in many areas of biology, given the significant roles these molecules play in cellular regulation. Two...
8.
Johnson D, Li W, Gordon D, Bhattacharjee A, Curry B, Ghosh J, et al.
Genome Res . 2008 Feb; 18(3):393-403. PMID: 18258921
The most widely used method for detecting genome-wide protein-DNA interactions is chromatin immunoprecipitation on tiling microarrays, commonly known as ChIP-chip. Here, we conducted the first objective analysis of tiling array...
9.
Ach R, Floore A, Curry B, Lazar V, Glas A, Pover R, et al.
BMC Genomics . 2007 Jun; 8:148. PMID: 17553173
Background: The increasing use of DNA microarrays in biomedical research, toxicogenomics, pharmaceutical development, and diagnostics has focused attention on the reproducibility and reliability of microarray measurements. While the reproducibility of...
10.
Wang H, Ach R, Curry B
RNA . 2006 Nov; 13(1):151-9. PMID: 17105992
We have developed a sensitive, accurate, and multiplexed microRNA (miRNA) profiling assay that is based on a highly efficient labeling method and novel microarray probe design. The probes provide both...