Blas Frangione
Overview
Explore the profile of Blas Frangione including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
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Articles
52
Citations
3728
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0
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Recent Articles
1.
Tarasoff-Conway J, Carare R, Osorio R, Glodzik L, Butler T, Fieremans E, et al.
Nat Rev Neurol
. 2016 Mar;
12(4):248.
PMID: 27020556
No abstract available.
2.
Tarasoff-Conway J, Carare R, Osorio R, Glodzik L, Butler T, Fieremans E, et al.
Nat Rev Neurol
. 2015 Jul;
11(8):457-70.
PMID: 26195256
Accumulation of toxic protein aggregates-amyloid-β (Aβ) plaques and hyperphosphorylated tau tangles-is the pathological hallmark of Alzheimer disease (AD). Aβ accumulation has been hypothesized to result from an imbalance between Aβ...
3.
Halliday M, Pomara N, Sagare A, Mack W, Frangione B, Zlokovic B
JAMA Neurol
. 2013 Sep;
70(9):1198-200.
PMID: 24030206
No abstract available.
4.
Osorio R, Pirraglia E, Aguera-Ortiz L, During E, Sacks H, Ayappa I, et al.
J Am Geriatr Soc
. 2011 Mar;
59(3):559-62.
PMID: 21391952
No abstract available.
5.
Tomidokoro Y, Tamaoka A, Holton J, Lashley T, Frangione B, Revesz T, et al.
Hirosaki Igaku
. 2010 Nov;
61(Suppl):S262-S269.
PMID: 21037969
Amyloid molecules harboring pyroglutamate (pGlu) residue at the N-termini are considered to be important for the development of cerebral amyloidosis such as Alzheimer's disease and thought to be either spontaneously...
6.
Ghiso J, Tomidokoro Y, Revesz T, Frangione B, Rostagno A
Hirosaki Igaku
. 2010 Nov;
61(Suppl):S111-S124.
PMID: 21037967
Cerebral amyloid angiopathy (CAA) is increasingly recognized as a major contributor of Alzheimer's disease (AD) pathogenesis. To date, vascular deposits and not parenchymal plaques appear more sensitive predictors of dementia....
7.
Tomidokoro Y, Rostagno A, Neubert T, Lu Y, Rebeck G, Frangione B, et al.
Am J Pathol
. 2010 Mar;
176(4):1841-54.
PMID: 20228223
Mutations within the amyloid-beta (Abeta) sequence, especially those clustered at residues 21-23, which are linked to early onset familial Alzheimer's disease (AD), are primarily associated with cerebral amyloid angiopathy (CAA)....
8.
Boutajangout A, Goni F, Knudsen E, Schreiber F, Asuni A, Quartermain D, et al.
J Alzheimers Dis
. 2009 Sep;
18(4):961-72.
PMID: 19749432
Immunotherapy holds great promise for Alzheimer's disease (AD) and other conformational disorders but certain adverse reactions need to be overcome. Prior to the side effects in the first Elan/Wyeth AD...
9.
Revesz T, Holton J, Lashley T, Plant G, Frangione B, Rostagno A, et al.
Acta Neuropathol
. 2009 Feb;
118(1):115-30.
PMID: 19225789
In cerebral amyloid angiopathy (CAA), amyloid fibrils deposit in walls of arteries, arterioles and less frequently in veins and capillaries of the central nervous system, often resulting in secondary degenerative...
10.
Trouche S, Asuni A, Rouland S, Wisniewski T, Frangione B, Verdier J, et al.
Vaccine
. 2008 Dec;
27(7):957-64.
PMID: 19114076
We have been developing Abeta derivative vaccines with the objective to improve the safety of Abeta targeting immunotherapy. Our Abeta homologs are designed to have less direct toxicity and to...