Bjorn P Pedersen
Overview
Explore the profile of Bjorn P Pedersen including associated specialties, affiliations and a list of published articles.
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17
Citations
999
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0
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Recent Articles
1.
Nel L, Thaysen K, Jamecna D, Olesen E, Szomek M, Langer J, et al.
Life Sci Alliance
. 2024 Oct;
8(1).
PMID: 39455279
In eukaryotes, integration of sterols into the vacuolar/lysosomal membrane is critically dependent on the Niemann-Pick type C (NPC) system. The system consists of an integral membrane protein, called NCR1 in...
2.
Tschernoster N, Erger F, Kohl S, Reusch B, Wenzel A, Walsh S, et al.
Genome Med
. 2023 Aug;
15(1):62.
PMID: 37612755
Background: Long-read sequencing is increasingly used to uncover structural variants in the human genome, both functionally neutral and deleterious. Structural variants occur more frequently in regions with a high homology...
3.
Sweet M, Larsen C, Zhang X, Schlame M, Pedersen B, Stokes D
Proc Natl Acad Sci U S A
. 2021 Jul;
118(29).
PMID: 34272288
KdpFABC is an oligomeric K transport complex in prokaryotes that maintains ionic homeostasis under stress conditions. The complex comprises a channel-like subunit (KdpA) from the superfamily of K transporters and...
4.
Sweet M, Zhang X, Erdjument-Bromage H, Dubey V, Khandelia H, Neubert T, et al.
Elife
. 2020 Sep;
9.
PMID: 32955430
KdpFABC is an ATP-dependent K pump that ensures bacterial survival in K-deficient environments. Whereas transcriptional activation of kdpFABC expression is well studied, a mechanism for down-regulation when K levels are...
5.
Pedersen B, Stokes D, Apell H
Mol Membr Biol
. 2019 Jul;
35(1):21-38.
PMID: 31259644
In bacteria, K is used to maintain cell volume and osmotic potential. Homeostasis normally involves a network of constitutively expressed transport systems, but in K deficient environments, the KdpFABC complex...
6.
Focht D, Croll T, Pedersen B, Nissen P
Front Physiol
. 2017 Apr;
8:202.
PMID: 28443028
The plasma membrane H-ATPase is a proton pump of the P-type ATPase family and essential in plants and fungi. It extrudes protons to regulate pH and maintains a strong proton-motive...
7.
Kapoor K, Finer-Moore J, Pedersen B, Caboni L, Waight A, Hillig R, et al.
Proc Natl Acad Sci U S A
. 2016 Apr;
113(17):4711-6.
PMID: 27078104
Cancerous cells have an acutely increased demand for energy, leading to increased levels of human glucose transporter 1 (hGLUT1). This up-regulation suggests hGLUT1 as a target for therapeutic inhibitors addressing...
8.
Tomasiak T, Pedersen B, Chaudhary S, Rodriguez A, Colmanares Y, Roe-Zurz Z, et al.
Curr Protoc Protein Sci
. 2014 Aug;
77:29.11.1-29.11.14.
PMID: 25081745
This unit describes rapid and generally applicable methods to identify conditions that stabilize membrane proteins using temperature-based denaturation measurements as a proxy for target time-dependent stability. Recent developments with thiol-reactive...
9.
Pedersen B, Ifrim G, Liboriussen P, Axelsen K, Palmgren M, Nissen P, et al.
PLoS One
. 2014 Jan;
9(1):e85139.
PMID: 24465495
Background: Structured Logistic Regression (SLR) is a newly developed machine learning tool first proposed in the context of text categorization. Current availability of extensive protein sequence databases calls for an...
10.
Pedersen B, Kumar H, Waight A, Risenmay A, Roe-Zurz Z, Chau B, et al.
Nature
. 2013 Apr;
496(7446):533-6.
PMID: 23542591
Phosphate is crucial for structural and metabolic needs, including nucleotide and lipid synthesis, signalling and chemical energy storage. Proton-coupled transporters of the major facilitator superfamily (MFS) are essential for phosphate...