Bjorn P Pedersen
Overview
Explore the profile of Bjorn P Pedersen including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
999
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0
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Recent Articles
11.
Chaudhary S, Pak J, Pedersen B, Bang L, Zhang L, Ngaw S, et al.
Methods
. 2011 Sep;
55(4):273-80.
PMID: 21925269
It is often an immense challenge to overexpress human membrane proteins at levels sufficient for structural studies. The use of Human Embryonic Kidney 293 (HEK 293) cells to express full-length...
12.
Morth J, Pedersen B, Buch-Pedersen M, Andersen J, Vilsen B, Palmgren M, et al.
Nat Rev Mol Cell Biol
. 2010 Dec;
12(1):60-70.
PMID: 21179061
Plasma membrane ATPases are primary active transporters of cations that maintain steep concentration gradients. The ion gradients and membrane potentials derived from them form the basis for a range of...
13.
Ekberg K, Pedersen B, Sorensen D, Nielsen A, Veierskov B, Nissen P, et al.
Proc Natl Acad Sci U S A
. 2010 Nov;
107(50):21400-5.
PMID: 21098259
The activity of P-type plasma membrane H(+)-ATPases is modulated by H(+) and cations, with K(+) and Ca(2+) being of physiological relevance. Using X-ray crystallography, we have located the binding site...
14.
Pedersen B, Morth J, Nissen P
Acta Crystallogr D Biol Crystallogr
. 2010 Feb;
66(Pt 3):309-13.
PMID: 20179343
An approach is presented for the structure determination of membrane proteins on the basis of poorly diffracting crystals which exploits molecular replacement for heavy-atom site identification at 6-9 A maximum...
15.
Yatime L, Buch-Pedersen M, Musgaard M, Morth J, Lund Winther A, Pedersen B, et al.
Biochim Biophys Acta
. 2009 Apr;
1787(4):207-20.
PMID: 19388138
P-type ATPases catalyze the selective active transport of ions like H+, Na+, K+, Ca2+, Zn2+, and Cu2+ across diverse biological membrane systems. Many members of the P-type ATPase protein family,...
16.
Pedersen B, Buch-Pedersen M, Morth J, Palmgren M, Nissen P
Nature
. 2007 Dec;
450(7172):1111-4.
PMID: 18075595
A prerequisite for life is the ability to maintain electrochemical imbalances across biomembranes. In all eukaryotes the plasma membrane potential and secondary transport systems are energized by the activity of...
17.
Morth J, Pedersen B, Toustrup-Jensen M, Sorensen T, Petersen J, Andersen J, et al.
Nature
. 2007 Dec;
450(7172):1043-9.
PMID: 18075585
The Na+,K+-ATPase generates electrochemical gradients for sodium and potassium that are vital to animal cells, exchanging three sodium ions for two potassium ions across the plasma membrane during each cycle...