Binoj C Nair
Overview
Explore the profile of Binoj C Nair including associated specialties, affiliations and a list of published articles.
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21
Citations
626
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Recent Articles
11.
Sareddy G, Nair B, Gonugunta V, Zhang Q, Brenner A, Brann D, et al.
Mol Cancer Ther
. 2012 Mar;
11(5):1174-82.
PMID: 22442308
Gliomas are the most common and devastating central nervous system neoplasms. A gender bias exists in their development: females are at lower risk than males, implicating estrogen-mediated protective effects. Estrogen...
12.
Nair B, Vallabhaneni S, Tekmal R, Vadlamudi R
Breast Cancer Res
. 2011 Aug;
13(3):R80.
PMID: 21834972
Introduction: Current clinical strategies for treating hormonal breast cancer involve the use of anti-estrogens that block estrogen receptor (ER)α functions and aromatase inhibitors that decrease local and systemic estrogen production....
13.
Gonugunta V, Nair B, Rajhans R, Sareddy G, Nair S, Vadlamudi R
PLoS One
. 2011 Jun;
6(6):e21095.
PMID: 21695158
Background: Proline-, glutamic acid-, and leucine-rich protein (PELP1) is a novel nuclear receptor coregulator with a multitude of functions. PELP1 serves as a scaffolding protein that couples various signaling complexes...
14.
Cortez V, Nair B, Chakravarty D, Vadlamudi R
Front Biosci (Schol Ed)
. 2011 Jan;
3(2):788-96.
PMID: 21196412
Integrin-linked kinase 1 (ILK1) is a serine/threonine kinase that plays important roles in a variety of cellular functions including cell survival, migration and angiogenesis. ILK1 is normally expressed in numerous...
15.
Vallabhaneni S, Nair B, Cortez V, Challa R, Chakravarty D, Tekmal R, et al.
Breast Cancer Res Treat
. 2010 Dec;
130(2):377-85.
PMID: 21184269
The estrogen receptor (ER) is implicated in the progression of breast cancer. Despite positive effects of hormonal therapy, initial or acquired resistance to endocrine therapies frequently occurs. Recent studies suggested...
16.
Nair B, Nair S, Chakravarty D, Challa R, Manavathi B, Yew P, et al.
Cancer Res
. 2010 Sep;
70(18):7166-75.
PMID: 20807815
Estrogen receptor (ER) signaling plays an important role in breast cancer progression, and ER functions are influenced by coregulatory proteins. PELP1 (proline-, glutamic acid-, and leucine-rich protein 1) is a...
17.
Chakravarty D, Nair S, Santhamma B, Nair B, Wang L, Bandyopadhyay A, et al.
Cancer Res
. 2010 May;
70(10):4092-101.
PMID: 20460518
The molecular basis of breast cancer progression to metastasis and the role of estrogen receptor (ER) signaling in this process remain poorly understood. Emerging evidence suggests that ER participates in...
18.
Nair S, Nair B, Cortez V, Chakravarty D, Metzger E, Schule R, et al.
EMBO Rep
. 2010 May;
11(6):438-44.
PMID: 20448663
Histone methylation has a key role in oestrogen receptor (ERalpha)-mediated transactivation of genes. Proline glutamic acid and leucine-rich protein 1 (PELP1) is a new proto-oncogene that functions as an ERalpha...
19.
20.
Vadlamudi R, Rajhans R, Chakravarty D, Nair B, Nair S, Evans D, et al.
J Steroid Biochem Mol Biol
. 2009 Oct;
118(4-5):211-8.
PMID: 19800002
Estradiol (E2), estrogen receptor (ER), ER-coregulators have been implicated in the development and progression of breast cancer. In situ E2 synthesis is implicated in tumor cell proliferation through autocrine or...