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Bin T Teh

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Articles 61
Citations 2423
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Recent Articles
11.
Hansel D, Zhang Z, Petillo D, Teh B
BMC Med Genomics . 2013 Oct; 6:42. PMID: 24134934
Background: Bladder cancer exists as several distinct subtypes, including urothelial carcinoma (UCa), squamous cell carcinoma (SCCa), adenocarcinoma and small cell carcinoma. These entities, despite showing distinct morphology and clinical behavior,...
12.
Bellmunt J, Teh B, Tortora G, Rosenberg J
Nat Rev Clin Oncol . 2013 Aug; 10(10):557-70. PMID: 23982523
As whole-genome sequencing technology rapidly advances, the insights gained from deciphering cancer genomes are shifting the paradigm in the diagnosis and treatment of cancer with the promise of individualized treatment...
13.
Zhou N, Singh K, Mir M, Parker Y, Lindner D, Dreicer R, et al.
Clin Cancer Res . 2013 Feb; 19(7):1717-28. PMID: 23403633
Purpose: Despite more than 70,000 new cases of bladder cancer in the United States annually, patients with advanced disease have a poor prognosis due to limited treatment modalities. We evaluated...
14.
Nahorski M, Seabra L, Straatman-Iwanowska A, Wingenfeld A, Reiman A, Lu X, et al.
Hum Mol Genet . 2012 Sep; 21(24):5268-79. PMID: 22965878
Inherited mutations in the folliculin (FLCN) gene cause the Birt-Hogg-Dubé syndrome of familial hair follicle tumours (fibrofolliculomas), lung cysts and kidney tumours. Though folliculin has features of a tumour suppressor,...
15.
Ho J, Metcalf J, Yan M, Turgeon P, Wang J, Chalsev M, et al.
J Biol Chem . 2012 Jun; 287(34):29003-20. PMID: 22745131
The processes by which cells sense and respond to ambient oxygen concentration are fundamental to cell survival and function, and they commonly target gene regulatory events. To date, however, little...
16.
Ding Y, Huang D, Zhang Z, Smith J, Petillo D, Looyenga B, et al.
Cancer Res . 2011 Jun; 71(15):5225-34. PMID: 21642374
In recent years, several molecularly targeted therapies have been approved for clear cell renal cell carcinoma (ccRCC), a highly aggressive cancer. Although these therapies significantly extend overall survival, nearly all...
17.
Roos F, Evans A, Brenner W, Wondergem B, Klomp J, Heir P, et al.
Am J Pathol . 2011 Feb; 178(2):853-60. PMID: 21281817
Molecular pathways associated with pathogenesis of sporadic papillary renal cell carcinoma (PRCC), the second most common form of kidney cancer, are poorly understood. We analyzed primary tumor specimens from 35...
18.
Witteveen J, Hamdy N, Dekkers O, Kievit J, van Wezel T, Teh B, et al.
Mod Pathol . 2011 Jan; 24(5):688-97. PMID: 21240254
Parathyroid carcinoma is associated with mutations in the HRPT2/CDC73 gene and with decreased parafibromin and calcium-sensing receptor (CASR) expression, but in some cases establishing an unequivocal diagnosis remains a challenge....
19.
Looyenga B, Furge K, Dykema K, Koeman J, Swiatek P, Giordano T, et al.
Proc Natl Acad Sci U S A . 2011 Jan; 108(4):1439-44. PMID: 21220347
The receptor tyrosine kinase MET is frequently amplified in human tumors, resulting in high cell surface densities and constitutive activation even in the absence of growth factor stimulation by its...
20.
Klomp J, Petillo D, Niemi N, Dykema K, Chen J, Yang X, et al.
BMC Med Genomics . 2010 Dec; 3:59. PMID: 21162720
Background: Germline mutations in the folliculin (FLCN) gene are associated with the development of Birt-Hogg-Dubé syndrome (BHDS), a disease characterized by papular skin lesions, a high occurrence of spontaneous pneumothorax,...