Deborah J Marsh
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Explore the profile of Deborah J Marsh including associated specialties, affiliations and a list of published articles.
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71
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1821
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Recent Articles
1.
Matthews B, Wong-Brown M, Liu D, Yee C, Dickson K, Schneider J, et al.
Mol Ther Oncol
. 2025 Jan;
32(4):200911.
PMID: 39802157
Drug repurposing has potential to improve outcomes for high-grade serous ovarian cancer (HGSOC). Repurposing drugs with PARP family binding activity may produce cytotoxic effects through the multiple mechanisms of PARP...
2.
Hill M, Stapleton S, Nguyen P, Sais D, Deutsch F, Gay V, et al.
Int J Biochem Cell Biol
. 2024 Nov;
178:106705.
PMID: 39615668
MicroRNAs (miRNA,miRs) are small noncoding RNAs that are ubiquitously expressed in all mammalian cells. Their primary function is the regulation of nascent RNA transcripts by direct binding to regions on...
3.
Field N, Dickson K, Nassif N, Marsh D
Cancer Lett
. 2024 Oct;
605:217282.
PMID: 39369768
Genetic mutations and epigenetic modifications affecting multiple cancer-related genes occur synergistically to drive tumorigenesis. Across a wide spectrum of cancers, pathogenic changes have been identified in members of the SWItch/Sucrose...
4.
Ma Y, Field N, Xie T, Briscas S, Kokinogoulis E, Skipper T, et al.
Cancers (Basel)
. 2024 Sep;
16(17).
PMID: 39272926
SWI/SNF (SWItch/Sucrose Non-Fermentable) is the most frequently mutated chromatin-remodelling complex in human malignancy, with over 20% of tumours having a mutation in a SWI/SNF complex member. Mutations in specific SWI/SNF...
5.
Gallagher S, Johnstone A, De Livera A, Marsh D, Walsh S
J Cancer Surviv
. 2024 Jul;
PMID: 39085555
Purpose: More women diagnosed with breast cancer (BC) are living with oncology treatment-induced hot flushes (HFs). This Australian-based survey explores why some women experience more severe or ongoing HF and...
6.
Cortesi M, Liu D, Yee C, Marsh D, Ford C
Sci Rep
. 2024 Jan;
14(1):906.
PMID: 38195610
No abstract available.
7.
Travis G, McGowan E, Simpson A, Marsh D, Nassif N
Cancers (Basel)
. 2023 Oct;
15(20).
PMID: 37894321
The phosphatase and tensin homolog deleted on chromosome 10 () is a well characterised tumour suppressor, playing a critical role in the maintenance of fundamental cellular processes including cell proliferation,...
8.
Cortesi M, Liu D, Yee C, Marsh D, Ford C
Sci Rep
. 2023 Sep;
13(1):15769.
PMID: 37737283
Computational models are becoming an increasingly valuable tool in biomedical research. Their accuracy and effectiveness, however, rely on the identification of suitable parameters and on appropriate validation of the in-silico...
9.
Dickson K, Field N, Blackman T, Ma Y, Xie T, Kurangil E, et al.
Hum Mol Genet
. 2023 Jun;
32(17):2704-2716.
PMID: 37369005
Engineering single base edits using CRISPR technology including specific deaminases and single-guide RNA (sgRNA) is a rapidly evolving field. Different types of base edits can be constructed, with cytidine base...
10.
Pitiyarachchi O, Lee Y, Sim H, Srirangan S, Mapagu C, Kirk J, et al.
Transl Oncol
. 2023 Feb;
31:101638.
PMID: 36805919
Background: Somatic pathogenic variants (PVs) in homologous recombination DNA repair (HR)-related genes found in high-grade serous ovarian carcinomas (HGSC) are not well-characterised in older patients (≥70 years). This may reflect...