Bibha Choudhary
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Explore the profile of Bibha Choudhary including associated specialties, affiliations and a list of published articles.
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80
Citations
1406
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Recent Articles
1.
Nirgude S, Desai S, Ravindran F, Mhatre A, Mahadeva R, Sharma S, et al.
Int Immunopharmacol
. 2025 Jan;
148:114127.
PMID: 39870007
ROS (Reactive Oxygen Species) has a dual role in tumorigenesis. Some cancers have high ROS conditions, and others have low ROS. TNBC thrives on high ROS compared to other Breast...
2.
Roy U, Sharma A, Sharma S, Dahal S, Kumari N, Desai S, et al.
Mol Cell Biol
. 2024 Nov;
44(12):590-606.
PMID: 39511874
One of the primary reasons behind the pathogenesis of T cell acute lymphoblastic leukemia (T-ALL) is the deregulation of the transcription factor . The exon 4 of harbors several driver...
3.
Roy U, Desai S, Kumari S, Bushra T, Choudhary B, Raghavan S
J Immunol
. 2024 Sep;
213(8):1125-1138.
PMID: 39269689
The process of Ag receptor diversity is initiated by RAGs consisting of RAG1 and RAG2 in developing lymphocytes. Besides its role as a sequence-specific nuclease during V(D)J recombination, RAGs can...
4.
Manjunath M, Ravindran F, Sharma S, Siddiqua H, Raghavan S, Choudhary B
Int J Mol Sci
. 2024 Jun;
25(12).
PMID: 38928195
Targeted cancer therapy aims to disrupt the functions of proteins that regulate cancer progression, mainly by using small molecule inhibitors (SMIs). SMIs exert their effect by modulating signalling pathways, organelle...
5.
Gopalakrishnan V, Roy U, Srivastava S, Kariya K, Sharma S, Javedakar S, et al.
Cell Mol Life Sci
. 2024 Jan;
81(1):21.
PMID: 38196006
BCL6 translocation is one of the most common chromosomal translocations in cancer and results in its enhanced expression in germinal center B cells. It involves the fusion of BCL6 with...
6.
Ravindran F, Mhatre A, Koroth J, Narayan S, Choudhary B
Life Sci
. 2023 Dec;
334:122224.
PMID: 38084671
Aim: To understand the epigenetic role of curcumin, a natural polyphenolic compound extracted from the spice Curcuma longa in inducing cytotoxicity in two molecularly distinct ovarian cancer cell lines: PA1...
7.
Kumari R, Roy U, Desai S, Mondal A, Nair R, Nilavar N, et al.
Biochem J
. 2023 Dec;
480(24):2061-2077.
PMID: 38084601
The stringent regulation of RAGs (Recombination activating genes), the site-specific endonuclease responsible for V(D)J recombination, is important to prevent genomic rearrangements and chromosomal translocations in lymphoid cells. In the present...
8.
Sahana N, Yadava S, Choudhary B, Ravindran F, Khatoon H, Kulkarni M
J Oral Maxillofac Pathol
. 2023 Nov;
27(3):489-493.
PMID: 38033976
Introduction: Despite advances in diagnostics and therapeutics, two-thirds of oral cancer patients present with advanced disease, which increases both the morbidity and mortality risk. Circulating tumour cells (CTCs) are released...
9.
Sharma N, Choudhary B
Biomolecules
. 2023 Nov;
13(11).
PMID: 38002311
Multiple myeloma (MM) is a dyscrasia of plasma cells (PCs) characterized by abnormal immunoglobulin (Ig) production. The disease remains incurable due to a multitude of mutations and structural abnormalities in...
10.
Kumari N, Das K, Sharma S, Dahal S, Desai S, Roy U, et al.
J Biol Chem
. 2023 Nov;
299(12):105431.
PMID: 37926284
t(8;14) translocation is the hallmark of Burkitt's lymphoma and results in c-MYC deregulation. During the translocation, c-MYC gene on chromosome 8 gets juxtaposed to the Ig switch regions on chromosome...