Bhopal Mohapatra
Overview
Explore the profile of Bhopal Mohapatra including associated specialties, affiliations and a list of published articles.
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18
Citations
328
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Recent Articles
11.
Raja S, Desale S, Mohapatra B, Luan H, Soni K, Zhang J, et al.
Oncotarget
. 2016 Feb;
7(9):10522-35.
PMID: 26859680
Targeted delivery of anticancer drugs to tumor cells using monoclonal antibodies against oncogenic cell surface receptors is an emerging therapeutic strategy. These strategies include drugs directly conjugated to monoclonal antibodies...
12.
Desale S, Raja S, Kim J, Mohapatra B, Soni K, Luan H, et al.
J Control Release
. 2015 Feb;
208:59-66.
PMID: 25660204
ErbB2-driven breast cancers constitute 20-25% of the cases diagnosed within the USA. The humanized anti-ErbB2 monoclonal antibody, Trastuzumab (Herceptin™; Genentech), with chemotherapy is the current standard of treatment. Novel agents...
13.
Bailey T, Luan H, Tom E, Bielecki T, Mohapatra B, Ahmad G, et al.
J Biol Chem
. 2014 Sep;
289(44):30443-30458.
PMID: 25225290
ErbB2 overexpression drives oncogenesis in 20-30% cases of breast cancer. Oncogenic potential of ErbB2 is linked to inefficient endocytic traffic into lysosomes and preferential recycling. However, regulation of ErbB2 recycling...
14.
Rafiq K, Kolpakov M, Seqqat R, Guo J, Guo X, Qi Z, et al.
Circulation
. 2014 Mar;
129(20):2031-43.
PMID: 24583314
Background: The proto-oncogene Casitas b-lineage lymphoma (c-Cbl) is an adaptor protein with an intrinsic E3 ubiquitin ligase activity that targets receptor and nonreceptor tyrosine kinases, resulting in their ubiquitination and...
15.
Protein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligases
Mohapatra B, Ahmad G, Nadeau S, Zutshi N, An W, Scheffe S, et al.
Biochim Biophys Acta
. 2012 Oct;
1833(1):122-39.
PMID: 23085373
Protein tyrosine kinases (PTKs) coordinate a broad spectrum of cellular responses to extracellular stimuli and cell-cell interactions during development, tissue homeostasis, and responses to environmental challenges. Thus, an understanding of...
16.
Ortega-Cava C, Raja S, Laiq Z, Bailey T, Luan H, Mohapatra B, et al.
J Carcinog
. 2011 Dec;
10:29.
PMID: 22190871
Background: Well over a quarter of human breast cancers are ErbB2-driven and constitute a distinct subtype with substantially poorer prognosis. Yet, there are substantial gaps in our understanding of how...
17.
Tu C, Ahmad G, Mohapatra B, Bhattacharyya S, Ortega-Cava C, Chung B, et al.
Bioarchitecture
. 2011 Aug;
1(1):45-48.
PMID: 21866262
ESCRT pathway proteins play a key role in sorting ubiquitinated membrane receptors towards lysosomes providing an important mechanism for attenuating cell surface receptor signaling. However, recent studies point to a...
18.
Naramura M, Nadeau S, Mohapatra B, Ahmad G, Mukhopadhyay C, Sattler M, et al.
Oncotarget
. 2011 Mar;
2(3):245-50.
PMID: 21422499
Casitas B-lineage lymphoma (Cbl) family proteins are evolutionarily-conserved attenuators of protein tyrosine kinase (PTK) signaling. Biochemical analyses over the past two decades have firmly established that the negative regulatory functions...