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Bernard Malissen

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Articles 273
Citations 16147
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Recent Articles
1.
Mougari S, Favede V, Predella C, Reynard O, Durand S, Mazelier M, et al.
Commun Biol . 2025 Jan; 8(1):57. PMID: 39814955
We have assessed antiviral activity and induction of protective immunity of fusion-inhibitory lipopeptides derived from the C-terminal heptad-repeat domain of SARS-CoV-2 spike glycoprotein in transgenic mice expressing human ACE2 (K18-hACE2)....
2.
Messaoud-Nacer Y, Culerier E, Rose S, Maillet I, Boussad R, Veront C, et al.
Allergy . 2024 Oct; 80(3):715-737. PMID: 39466641
Background: Severe refractory, neutrophilic asthma remains an unsolved clinical problem. STING agonists induce a neutrophilic response in the airways, suggesting that STING activation may contribute to the triggering of neutrophilic...
3.
Goris M, Passelli K, Peyvandi S, Diaz-Varela M, Billion O, Prat-Luri B, et al.
PLoS Pathog . 2024 Sep; 20(9):e1012527. PMID: 39250503
Intracellular pathogens that replicate in host myeloid cells have devised ways to inhibit the cell's killing machinery. Pyroptosis is one of the host strategies used to reduce the pathogen replicating...
4.
Ozaki F, Ueno T, Kondo S, Kaneda M, Mizushima I, Yamada K, et al.
Cureus . 2024 Sep; 16(7):e65791. PMID: 39219918
Objective: Immunoglobulin G4-related disease (IgG4-RD) is a systemic inflammatory condition affecting multiple organs, including the pancreas, salivary glands, lungs, kidneys, skin, and lymph nodes. Clinically, it is characterized by elevated...
5.
de Greef P, Njeru S, Benz C, Fillatreau S, Malissen B, Agenes F, et al.
Sci Adv . 2024 Jul; 10(30):eadl0796. PMID: 39047099
Naive T cells recirculate between the spleen and lymph nodes where they mount immune responses when meeting dendritic cells presenting foreign antigen. As this may happen anywhere, naive T cells...
6.
Cadiou G, Beauvais T, Marotte L, Lambot S, Deleine C, Vignes C, et al.
Oncoimmunology . 2024 Jul; 13(1):2376782. PMID: 38983599
Immune checkpoint (IC) blockade and adoptive transfer of tumor-specific T-cells (ACT) are two major strategies to treat metastatic melanoma. Their combination can potentiate T-cell activation in the suppressive tumor microenvironment,...
7.
Oliveira L, Silva M, Gomes A, Santos R, Cardoso M, Novoa A, et al.
Nat Commun . 2024 May; 15(1):4119. PMID: 38750020
Sepsis results from systemic, dysregulated inflammatory responses to infection, culminating in multiple organ failure. Here, we demonstrate the utility of CD5L for treating experimental sepsis caused by cecal ligation and...
8.
Zamani M, Hadzima M, Blazkova K, Subr V, Ormsby T, Celis-Gutierrez J, et al.
J Biol Chem . 2024 Apr; 300(6):107325. PMID: 38685532
Immune checkpoint blockade (ICB) using monoclonal antibodies against programmed cell death protein 1 (PD-1) or programmed death-ligand 1 (PD-L1) is the treatment of choice for cancer immunotherapy. However, low tissue...
9.
James J, Coelho A, Lahore G, Hernandez C, Forster F, Malissen B, et al.
Antioxidants (Basel) . 2024 Apr; 13(4). PMID: 38671946
The positional cloning of single nucleotide polymorphisms (SNPs) of the neutrophil cytosolic factor 1 () gene, advocating that a low oxidative burst drives autoimmune disease, demands an understanding of the...
10.
Materna M, Delmonte O, Bosticardo M, Momenilandi M, Conrey P, Charmeteau-De Muylder B, et al.
Science . 2024 Feb; 383(6686):eadh4059. PMID: 38422122
We describe humans with rare biallelic loss-of-function variants impairing pre-α T cell receptor (pre-TCRα) expression. Low circulating naive αβ T cell counts at birth persisted over time, with normal memory...